Literature DB >> 25439750

Point of care coagulation testing in neurosurgery.

Christopher Beynon1, Andreas W Unterberg2, Oliver W Sakowitz2.   

Abstract

Impaired haemostasis represents a major risk factor for bleeding complications in neurosurgical patients. Coagulopathy commonly occurs after (brain) trauma and major haemorrhage or originates from antithrombotic medication. Point of care (POC) devices for bedside assessment of haemostatic parameters are increasingly used in various medical specialties. Results can be instantly implemented into treatment modalities as results are delivered within a very short period. POC coagulation testing has also shown beneficial effects in the treatment of neurosurgical patients. Identification of hyperfibrinolysis is achieved through viscoelastic testing of haemostasis and bedside coagulometry hastens the management of anticoagulated patients in need of urgent neurosurgical procedures. Results of POC testing of platelet function have been correlated with patient outcomes after traumatic brain injury and furthermore, quantification of antiplatelet medication effects on platelet activity is made possible through the use of these devices. Further studies are needed to characterise the potential of POC testing of platelet function. Antiplatelet medication plays an important role in regard to haemorrhagic and thromboembolic risks. Therefore, POC testing of platelet activity may improve treatment modalities in patients undergoing neurosurgical procedures as well as neurointerventional procedures (such as intracranial stent placement). In this article we summarise the available data of POC testing in neurosurgical patients and discuss the potential of these devices in this field. POC technologies have improved patient care in various medical fields and in our view it is likely that this will also apply to the field of neurosurgery.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antithrombotic medication; Bedside technique; Haemostasis; Intracranial haemorrhage; Neurosurgical emergency

Mesh:

Substances:

Year:  2014        PMID: 25439750     DOI: 10.1016/j.jocn.2014.07.029

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  4 in total

1.  Assessment of Platelet Function in Traumatic Brain Injury-A Retrospective Observational Study in the Neuro-Critical Care Setting.

Authors:  Caroline Lindblad; Eric Peter Thelin; Michael Nekludov; Arvid Frostell; David W Nelson; Mikael Svensson; Bo-Michael Bellander
Journal:  Front Neurol       Date:  2018-01-26       Impact factor: 4.003

2.  Point-of-care testing in the acute management of traumatic brain injury: Identifying the coagulopathic patient.

Authors:  Yair M Gozal; Christopher P Carroll; Bryan M Krueger; Jane Khoury; Norberto O Andaluz
Journal:  Surg Neurol Int       Date:  2017-04-05

3.  Implementation of Thromboelastometry for Coagulation Management in Isolated Traumatic Brain Injury Patients Undergoing Craniotomy.

Authors:  Marius Rimaitis; Diana Bilskienė; Tomas Tamošuitis; Rimantas Vilcinis; Kęstutis Rimaitis; Andrius Macas
Journal:  Med Sci Monit       Date:  2020-07-04

4.  Assessment of Haemostasis in patients undergoing emergent neurosurgery by rotational Elastometry and standard coagulation tests: a prospective observational study.

Authors:  Christoph Ellenberger; Najia Garofano; Gleicy Barcelos; John Diaper; Gordana Pavlovic; Marc Licker
Journal:  BMC Anesthesiol       Date:  2017-10-24       Impact factor: 2.217

  4 in total

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