Whittney A Warren1, Ronald J Markert2, Elizabeth D Stewart3. 1. Internal Medicine Residency, Boonshoft School of Medicine at WSU; Wright-Patterson Medical Center, Wright-Patterson Air Force Base. Electronic address: Whittney.Warren@gmail.com. 2. Internal Medicine Residency, Boonshoft School of Medicine at WSU. 3. Wright-Patterson Medical Center, Wright-Patterson Air Force Base.
Abstract
OBJECTIVE: In areas with endemic histoplasmosis, incidental pulmonary nodules are common. Rate of malignancy and applicability of current tracking guidelines in these regions remain unclear. METHODS: A total of 148 cases of incidental pulmonary nodules tracked with chest computed tomography were reviewed for radiologic characteristics, diagnosis, number, and size. RESULTS: Of the nodules, 87.8% were benign and 12.2% malignant; 30% of nodules >20mm were malignant. Number of nodules (P=.14) and granulomatous disease (P=.71) were not related to malignant diagnosis. CONCLUSION: Malignancy was lower than expected in nodules >20mm. Appropriate tracking guidelines for incidentally discovered nodules in histoplasmosis endemic regions must be determined. Published by Elsevier Inc.
OBJECTIVE: In areas with endemic histoplasmosis, incidental pulmonary nodules are common. Rate of malignancy and applicability of current tracking guidelines in these regions remain unclear. METHODS: A total of 148 cases of incidental pulmonary nodules tracked with chest computed tomography were reviewed for radiologic characteristics, diagnosis, number, and size. RESULTS: Of the nodules, 87.8% were benign and 12.2% malignant; 30% of nodules >20mm were malignant. Number of nodules (P=.14) and granulomatous disease (P=.71) were not related to malignant diagnosis. CONCLUSION:Malignancy was lower than expected in nodules >20mm. Appropriate tracking guidelines for incidentally discovered nodules in histoplasmosis endemic regions must be determined. Published by Elsevier Inc.
Authors: Johanna Uthoff; Prashant Nagpal; Rolando Sanchez; Thomas J Gross; Changhyun Lee; Jessica C Sieren Journal: Transl Lung Cancer Res Date: 2019-12