| Literature DB >> 25438615 |
Abstract
TIM proteins are known to promote viral entry into host cells. Unexpectedly, a recent study has shown that TIM proteins also inhibit HIV-1 release from the host cell by directly binding to phosphatidylserine exposed on the virus surface, providing details on a new role of TIM proteins in HIV replication.Entities:
Keywords: HIV; TIM; phosphatidylserine (PS)
Mesh:
Substances:
Year: 2014 PMID: 25438615 DOI: 10.1016/j.tim.2014.09.008
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079