Literature DB >> 25436729

Adipose tissue inflammation and metabolic dysfunction: a clinical perspective.

Charmaine S Tam1, Leanne M Redman.   

Abstract

Obesity is characterized by a state of chronic low-grade inflammation due to increased immune cells, specifically infiltrated macrophages into adipose tissue, which in turn secrete a range of proinflammatory mediators. This nonselective low-grade inflammation of adipose tissue is systemic in nature and can impair insulin signaling pathways, thus, increasing the risk of developing insulin resistance and type 2 diabetes. The aim of this review is to provide an update on clinical studies examining the role of adipose tissue in the development of obesity-associated complications in humans. We will discuss adipose tissue inflammation during different scenarios of energy imbalance and metabolic dysfunction including obesity and overfeeding, weight loss by calorie restriction or bariatric surgery, and conditions of insulin resistance (diabetes, polycystic ovarian syndrome).

Entities:  

Mesh：

Year:  2013        PMID： 25436729      PMCID： PMC6913892          DOI： 10.1515/hmbci-2013-0032

Source DB:  PubMed          Journal:  Horm Mol Biol Clin Investig        ISSN： 1868-1883


  42 in total

Review 1.  Inflammatory mechanisms in obesity.

Authors:  Margaret F Gregor; Gökhan S Hotamisligil
Journal:  Annu Rev Immunol       Date:  2011       Impact factor: 28.527

2.  Molecular inflammation and adipose tissue matrix remodeling precede physiological adaptations to pregnancy.

Authors:  Veronica Resi; Subhabrata Basu; Maricela Haghiac; Larraine Presley; Judi Minium; Bram Kaufman; Steven Bernard; Patrick Catalano; Sylvie Hauguel-de Mouzon
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-07-17       Impact factor: 4.310

3.  Low-dose rosiglitazone exerts an antiinflammatory effect with an increase in adiponectin independently of free fatty acid fall and insulin sensitization in obese type 2 diabetics.

Authors:  Husam Ghanim; Sandeep Dhindsa; Ahmad Aljada; Ajay Chaudhuri; Prabhakar Viswanathan; Paresh Dandona
Journal:  J Clin Endocrinol Metab       Date:  2006-06-27       Impact factor: 5.958

Review 4.  The effect of weight loss on C-reactive protein: a systematic review.

Authors:  Elizabeth Selvin; Nina P Paynter; Thomas P Erlinger
Journal:  Arch Intern Med       Date:  2007-01-08

5.  Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects.

Authors:  Karine Clément; Nathalie Viguerie; Christine Poitou; Claire Carette; Véronique Pelloux; Cyrile A Curat; Audrey Sicard; Sophie Rome; Arriel Benis; Jean-Daniel Zucker; Hubert Vidal; Martine Laville; Gregory S Barsh; Arnaud Basdevant; Vladimir Stich; Raffaella Cancello; Dominique Langin
Journal:  FASEB J       Date:  2004-11       Impact factor: 5.191

6.  Serum and follicular fluid cytokines in polycystic ovary syndrome during stimulated cycles.

Authors:  Giovanni Amato; Marisa Conte; Gherardo Mazziotti; Eleonora Lalli; Gabriella Vitolo; Arthur T Tucker; Antonio Bellastella; Carlo Carella; Alfredo Izzo
Journal:  Obstet Gynecol       Date:  2003-06       Impact factor: 7.661

7.  Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity.

Authors:  John M Wentworth; Gaetano Naselli; Wendy A Brown; Lisa Doyle; Belinda Phipson; Gordon K Smyth; Martin Wabitsch; Paul E O'Brien; Leonard C Harrison
Journal:  Diabetes       Date:  2010-03-31       Impact factor: 9.461

Review 8.  Mediators of low-grade chronic inflammation in polycystic ovary syndrome (PCOS).

Authors:  Miriam Ojeda-Ojeda; Mora Murri; María Insenser; Héctor F Escobar-Morreale
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

9.  B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.

Authors:  Jason DeFuria; Anna C Belkina; Madhumita Jagannathan-Bogdan; Jennifer Snyder-Cappione; Jordan David Carr; Yanina R Nersesova; Douglas Markham; Katherine J Strissel; Amanda A Watkins; Min Zhu; Jessica Allen; Jacqueline Bouchard; Gianluca Toraldo; Ravi Jasuja; Martin S Obin; Marie E McDonnell; Caroline Apovian; Gerald V Denis; Barbara S Nikolajczyk
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-11       Impact factor: 11.205

10.  Weight cycling enhances adipose tissue inflammatory responses in male mice.

Authors:  Sandra Barbosa-da-Silva; Julio C Fraulob-Aquino; Jessica R Lopes; Carlos A Mandarim-de-Lacerda; Marcia B Aguila
Journal:  PLoS One       Date:  2012-07-25       Impact factor: 3.240
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  7 in total

Review 1.  Role of Adipose Tissue Derived Exosomes in Metabolic Disease.

Authors:  RuiYan Mei; WeiWei Qin; YanHua Zheng; Zhuo Wan; Li Liu
Journal:  Front Endocrinol (Lausanne)       Date:  2022-05-04       Impact factor: 6.055

2.  Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging.

Authors:  Sindre Lee; Frode Norheim; Torgrim M Langleite; Hans J Noreng; Trygve H Storås; Lydia A Afman; Gary Frost; Jimmy D Bell; E Louise Thomas; Kristoffer J Kolnes; Daniel S Tangen; Hans K Stadheim; Gregor D Gilfillan; Hanne L Gulseth; Kåre I Birkeland; Jørgen Jensen; Christian A Drevon; Torgeir Holen
Journal:  Physiol Rep       Date:  2016-11

3.  CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance.

Authors:  Xiaoxiang Tian; Chenghui Yan; Meili Liu; Quanyu Zhang; Dan Liu; Yanxia Liu; Shaohua Li; Yaling Han
Journal:  PLoS One       Date:  2017-05-01       Impact factor: 3.240

Review 4.  Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines.

Authors:  Irene Maeve Rea; David S Gibson; Victoria McGilligan; Susan E McNerlan; H Denis Alexander; Owen A Ross
Journal:  Front Immunol       Date:  2018-04-09       Impact factor: 7.561

5.  Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity.

Authors:  Roel A van der Heijden; Martine C Morrison; Fareeba Sheedfar; Petra Mulder; Marijke Schreurs; Pascal P H Hommelberg; Marten H Hofker; Casper Schalkwijk; Robert Kleemann; Uwe J F Tietge; Debby P Y Koonen; Peter Heeringa
Journal:  Mediators Inflamm       Date:  2016-06-06       Impact factor: 4.711

6.  Circulating levels of Meteorin-like protein in polycystic ovary syndrome: A case-control study.

Authors:  Fatima Zahraa Fouani; Reza Fadaei; Nariman Moradi; Zahra Zandieh; Soheila Ansaripour; Mir Saeed Yekaninejad; Akram Vatannejad; Maryam Mahmoudi
Journal:  PLoS One       Date:  2020-04-24       Impact factor: 3.240

Review 7.  Anti-Inflammatory Nutrients and Obesity-Associated Metabolic-Inflammation: State of the Art and Future Direction.

Authors:  Giuseppe Grosso; Daniela Laudisio; Evelyn Frias-Toral; Luigi Barrea; Giovanna Muscogiuri; Silvia Savastano; Annamaria Colao
Journal:  Nutrients       Date:  2022-03-08       Impact factor: 5.717
  7 in total

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