Literature DB >> 25436382

Safety and survival benefit of surgical management for elderly gastric cancer patients.

Yan-Mei Bi, Xin-Zu Chen, Cheng-Kun Jing, Ru-Bai Zhou, Yu-Fei Gao, Li-Bo Yang, Xiao-Long Chen, Kun Yang, Bo Zhang, Zhi-Xin Chen, Jia-Ping Chen, Zong-Guang Zhou, Jian-Kun Hu.   

Abstract

OBJECTIVE: To study the safety and survival outcome of surgical management for elderly gastric cancer patients.
Methods: Patients proven of gastric cancer who aged ≥80 years during November 2002 to July 2011 were retrospectively analyzed. The detailed information of patients’ characteristics and surgical management was retrieved. Follow-up of overall survival status was performed to analyze the surgical effectiveness.
RESULTS: Totally, 92 (48 in surgery and 44 in non-surgery group) out of 187 eligible patients recorded adequate information and analyzed finally. There were 34 patients undergone radical gastrectomy, 6 palliative gastrectomy, 1 gastrojejunostomy and 7 exploratory laparotomy. Median follow-up durations were 25 (9-111) and 28 (8-114) months in surgery and non-surgery groups, respectively (p=0.797). Clinical-pathological T stage and node status were comparable. Clinical-pathological distal metastasis status was 15 and 26 M1 cases for surgery and nonsurgery, respectively (p=0.006). Incidence of postoperative complications and hospital mortality were 25.0% and 2.1%, respectively. The 2-year survival rates of M0 subgroups were 35.7% and 0% for surgery and nonesurgery, respectively (HR=3.98, p=0.022).
CONCLUSIONS: The safety of surgery for well-selected ≥ 80-year elderly gastric cancer patients was potentially acceptable and the patients of early or locally advanced diseases could obtain survival benefits by surgery.

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Mesh:

Year:  2014        PMID: 25436382

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  2 in total

1.  Way forward: Geriatric frailty assessment as risk predictor in gastric cancer surgery.

Authors:  Juul Jw Tegels; Jan Hmb Stoot
Journal:  World J Gastrointest Surg       Date:  2015-10-27

2.  Short and long-term outcomes after gastrectomy for gastric carcinoma in elderly patients.

Authors:  Bo Shu; Sanlin Lei; Fazhao Li; Songwen Hua; Yong Chen; Zhi Huo
Journal:  Int J Clin Exp Med       Date:  2015-08-15
  2 in total

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