Literature DB >> 25434743

Sphingolipids in the DNA damage response.

Brittany Carroll1, Jane Catalina Donaldson1, Lina Obeid2.   

Abstract

Recently, sphingolipid metabolizing enzymes have emerged as important targets of many chemotherapeutics and DNA damaging agents and therefore play significant roles in mediating the physiological response of the cell to DNA damage. In this review we will highlight points of connection between the DNA damage response (DDR) and sphingolipid metabolism; specifically how certain sphingolipid enzymes are regulated in response to DNA damage and how the bioactive lipids produced by these enzymes affect cell fate. Published by Elsevier Ltd.

Entities:  

Keywords:  Ceramide; DNA damage; Sphingosine; Sphingosine 1-phosphate

Mesh：

Substances：

Year:  2014        PMID： 25434743      PMCID： PMC4425997          DOI： 10.1016/j.jbior.2014.11.001

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN： 2212-4926


  121 in total

1.  Molecular cloning and characterization of a human mitochondrial ceramidase.

Authors:  S El Bawab; P Roddy; T Qian; A Bielawska; J J Lemasters; Y A Hannun
Journal:  J Biol Chem       Date:  2000-07-14       Impact factor: 5.157

Review 2.  DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis.

Authors:  G K Dasika; S C Lin; S Zhao; P Sung; A Tomkinson; E Y Lee
Journal:  Oncogene       Date:  1999-12-20       Impact factor: 9.867

3.  Surfing the p53 network.

Authors:  B Vogelstein; D Lane; A J Levine
Journal:  Nature       Date:  2000-11-16       Impact factor: 49.962

4.  Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase.

Authors:  K Hofmann; S Tomiuk; G Wolff; W Stoffel
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

5.  Stress-induced apoptosis is not mediated by endolysosomal ceramide.

Authors:  B Ségui; C Bezombes; E Uro-Coste; J A Medin; N Andrieu-Abadie; N Augé; A Brouchet; G Laurent; R Salvayre; J P Jaffrézou; T Levade
Journal:  FASEB J       Date:  2000-01       Impact factor: 5.191

6.  Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

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Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-05       Impact factor: 11.205

7.  Human acid ceramidase is overexpressed but not mutated in prostate cancer.

Authors:  R S Seelan; C Qian; A Yokomizo; D G Bostwick; D I Smith; W Liu
Journal:  Genes Chromosomes Cancer       Date:  2000-10       Impact factor: 5.006

8.  Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent.

Authors:  S S Metkar; M Anand; P P Manna; K N Naresh; J J Nadkarni
Journal:  Exp Cell Res       Date:  2000-02-25       Impact factor: 3.905

Review 9.  Secretory sphingomyelinase.

Authors:  I Tabas
Journal:  Chem Phys Lipids       Date:  1999-11       Impact factor: 3.329

10.  Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.

Authors:  H Liu; M Sugiura; V E Nava; L C Edsall; K Kono; S Poulton; S Milstien; T Kohama; S Spiegel
Journal:  J Biol Chem       Date:  2000-06-30       Impact factor: 5.157
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  21 in total

Review 1.  Ceramidases, roles in sphingolipid metabolism and in health and disease.

Authors:  Nicolas Coant; Wataru Sakamoto; Cungui Mao; Yusuf A Hannun
Journal:  Adv Biol Regul       Date:  2016-10-11

Review 2.  DNA damage response and sphingolipid signaling in liver diseases.

Authors:  Masayuki Nagahashi; Yasunobu Matsuda; Kazuki Moro; Junko Tsuchida; Daiki Soma; Yuki Hirose; Takashi Kobayashi; Shin-Ichi Kosugi; Kazuaki Takabe; Masaaki Komatsu; Toshifumi Wakai
Journal:  Surg Today       Date:  2015-10-29       Impact factor: 2.549

Review 3.  Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era.

Authors:  Jeremy Shaw; Pedro Costa-Pinheiro; Logan Patterson; Kelly Drews; Sarah Spiegel; Mark Kester
Journal:  Adv Cancer Res       Date:  2018-06-19       Impact factor: 6.242

Review 4.  Ceramide Signaling and p53 Pathways.

Authors:  Kristen A Jeffries; Natalia I Krupenko
Journal:  Adv Cancer Res       Date:  2018-06-01       Impact factor: 6.242

Review 5.  Sphingolipids in neutrophil function and inflammatory responses: Mechanisms and implications for intestinal immunity and inflammation in ulcerative colitis.

Authors:  Mel Pilar Espaillat; Richard R Kew; Lina M Obeid
Journal:  Adv Biol Regul       Date:  2016-11-14

6.  A link between very long chain fatty acid elongation and mating-specific yeast cell cycle arrest.

Authors:  Michelle L Villasmil; Christina Gallo-Ebert; Hsing-Yin Liu; Jamie Francisco; Joseph T Nickels
Journal:  Cell Cycle       Date:  2017-09-07       Impact factor: 4.534

7.  Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle.

Authors:  Larissa Alexsandra da Silva Neto Trajano; Eduardo Tavares Lima Trajano; Luiz Philippe da Silva Sergio; Adilson Fonseca Teixeira; Andre Luiz Mencalha; Ana Carolina Stumbo; Adenilson de Souza da Fonseca
Journal:  Lasers Med Sci       Date:  2018-04-26       Impact factor: 3.161

Review 8.  Dysregulation of lysophospholipid signaling by p53 in malignant cells and the tumor microenvironment.

Authors:  Sue Chin Lee; Kuan-Hung Lin; Andrea Balogh; Derek D Norman; Mitul Bavaria; Bryan Kuo; Junming Yue; Louisa Balázs; Zoltán Benyó; Gábor Tigyi
Journal:  Cell Signal       Date:  2020-11-28       Impact factor: 4.315

Review 9.  Role of Inositol Phosphosphingolipid Phospholipase C1, the Yeast Homolog of Neutral Sphingomyelinases in DNA Damage Response and Diseases.

Authors:  Kaushlendra Tripathi
Journal:  J Lipids       Date:  2015-08-06

10.  Drug-resistance in doxorubicin-resistant FL5.12 hematopoietic cells: elevated MDR1, drug efflux and side-population positive and decreased BCL2-family member expression.

Authors:  Linda S Steelman; Steve L Abrams; Peter Ruvolo; Vivian Ruvolo; Lucio Cocco; Stefano Ratti; Alberto M Martelli; Luca M Neri; Saverio Candido; Massimo Libra; James A McCubrey
Journal:  Oncotarget       Date:  2017-12-06
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