Weiguang Wang1, Weixun Duan1, Yang Xue2, Ling Wang3, Jincheng Liu1, Shiqiang Yu4, Dinghua Yi1. 1. Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China. 2. State Key Laboratory of Military Stomatology, Department of Oral Biology, School of Stomatology, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China. 3. Department of Health Statistics, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China. 4. Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China. Electronic address: yidh@fmmu.edu.cn.
Abstract
OBJECTIVE: To establish a systematic registry of aortic dissection in China, assess the clinical features of Chinese patients with acute aortic dissection (AAD), and compare our results with the data published by the International Registry of Acute Aortic Dissection (IRAD). METHODS: We established the first Registry of Aortic Dissection in China (Sino-RAD) in 2011. Then we evaluated 1003 patients with AAD in Sino-RAD and compared our results with those reported by IRAD. RESULTS: Compared with IRAD, the patients with AAD in Sino-RAD were significantly younger. Also, the ratio of male patients in Sino-RAD was significantly greater for the total cohort and the type A and B cohorts. The overall in-hospital mortality was 10.3% in Sino-RAD. For type A dissection, more patients in Sino-RAD received medical treatment and fewer received surgical treatment. The overall mortality, mortality of medical treatment, and mortality of surgical treatment was lower in Sino-RAD. In type B dissection, fewer patients in Sino-RAD received medical and surgical treatment and more received endovascular treatment. CONCLUSIONS: The first Sino-RAD, including 15 large cardiovascular centers throughout China, was established. Our data were compared with those reported by IRAD. We found that, compared with Western populations, Chinese patients with AAD showed 6 differences, including earlier onset, more male patients, a low incidence of hypertension, a low incidence of chest pain, a high incidence of back pain, great differences in the choice of therapeutic strategies, and relatively low in-hospital mortality.
OBJECTIVE: To establish a systematic registry of aortic dissection in China, assess the clinical features of Chinese patients with acute aortic dissection (AAD), and compare our results with the data published by the International Registry of Acute Aortic Dissection (IRAD). METHODS: We established the first Registry of Aortic Dissection in China (Sino-RAD) in 2011. Then we evaluated 1003 patients with AAD in Sino-RAD and compared our results with those reported by IRAD. RESULTS: Compared with IRAD, the patients with AAD in Sino-RAD were significantly younger. Also, the ratio of male patients in Sino-RAD was significantly greater for the total cohort and the type A and B cohorts. The overall in-hospital mortality was 10.3% in Sino-RAD. For type A dissection, more patients in Sino-RAD received medical treatment and fewer received surgical treatment. The overall mortality, mortality of medical treatment, and mortality of surgical treatment was lower in Sino-RAD. In type B dissection, fewer patients in Sino-RAD received medical and surgical treatment and more received endovascular treatment. CONCLUSIONS: The first Sino-RAD, including 15 large cardiovascular centers throughout China, was established. Our data were compared with those reported by IRAD. We found that, compared with Western populations, Chinese patients with AAD showed 6 differences, including earlier onset, more male patients, a low incidence of hypertension, a low incidence of chest pain, a high incidence of back pain, great differences in the choice of therapeutic strategies, and relatively low in-hospital mortality.
Authors: Matthew D Solomon; Thomas Leong; Sue Hee Sung; Catherine Lee; J Geoff Allen; Joseph Huh; Paul LaPunzina; Hon Lee; Duncan Mason; Vicken Melikian; Daniel Pellegrini; David Scoville; Ahmad Y Sheikh; Dorinna Mendoza; Sahar Naderi; Ann Sheridan; Xinge Hu; Wendy Cirimele; Anne Gisslow; Sandy Leung; Kristine Padilla; Michael Bloom; Josh Chung; Adrienne Topic; Paniz Vafaei; Robert Chang; D Craig Miller; David H Liang; Alan S Go Journal: JAMA Cardiol Date: 2022-10-05 Impact factor: 30.154