| Literature DB >> 25432732 |
Abstract
Gait disorders are frequently accompanied by loss of balance and falls, and are a common cause of disability, particularly among the elderly. In many cases the cause is multifactorial, involving both neurologic and nonneurologic systems. Physical therapy and training, coupled with pharmacologic and surgical therapy, can usually provide some improvement in ambulation, which translates into better quality of life. More research is needed on the mechanisms of gait and its disorders as well as on symptomatic therapies. Better understanding of the pathophysiology of gait disorders should lead to more specific, pathogenesis-targeted therapies.Entities:
Keywords: Ataxia; Basal ganglia; Bradykinesia; Freezing of gait; Gait; Parkinson disease; Parkinsonism; Progressive supranuclear palsy
Mesh:
Year: 2015 PMID: 25432732 DOI: 10.1016/j.ncl.2014.09.007
Source DB: PubMed Journal: Neurol Clin ISSN: 0733-8619 Impact factor: 3.806