Literature DB >> 25431654

Development of a Concise Synthetic Approach to Access Oroxin A.

Haijun Chen1, Guihua He2, Cailong Li2, Longrong Dong2, Xiaobo Xie2, Jianlei Wu2, Yu Gao2, Jia Zhou3.   

Abstract

A novel environment-friendly method to access bioactive oroxin A through a one-pot/two-step process from naturally abundant and inexpensive baicalin is described. The procedure presented here has several advantages including clean, one-pot, synthetic ease, and large-scale feasibility. This work also provides a model strategy for rapid and diverse access to natural molecules sharing the common skeleton of this family.

Entities:  

Year:  2014        PMID： 25431654      PMCID： PMC4242426          DOI： 10.1039/C4RA08573F

Source DB:  PubMed          Journal:  RSC Adv        ISSN： 2046-2069            Impact factor:   3.361


  23 in total

1.  [CHEMICAL STUDIES ON OROXYLEUM INDICUM (L.) VENT. I. TWO NEW FLAVONE GLUCOSIDES OROXIN A AND OROXIN B].

Authors:  C L CHENG; T Y CHAO
Journal:  Yao Xue Xue Bao       Date:  1964-11

2.  Preparative isolation of flavonoid compounds from Oroxylum indicum by high-speed counter-current chromatography by using ionic liquids as the modifier of two-phase solvent system.

Authors:  Renmin Liu; Lili Xu; Aifeng Li; Ailing Sun
Journal:  J Sep Sci       Date:  2010-04       Impact factor: 3.645

Review 3.  The evolving role of natural products in drug discovery.

Authors:  Frank E Koehn; Guy T Carter
Journal:  Nat Rev Drug Discov       Date:  2005-03       Impact factor: 84.694

Review 4.  Impact of natural products on developing new anti-cancer agents.

Authors:  Gordon M Cragg; Paul G Grothaus; David J Newman
Journal:  Chem Rev       Date:  2009-07       Impact factor: 60.622

5.  [Linear scale-up of the separation of active components from Oroxylum indicum using high-speed counter-current chromatography].

Authors:  Yuan Yuan; Houding Luo; Lijuan Chen
Journal:  Se Pu       Date:  2008-07

6.  Flavonoids of Enhydra fluctuans exhibit anticancer activity against Ehrlich's ascites carcinoma in mice.

Authors:  Santanu Sannigrahi; Upal Kanti Mazumder; Arijit Mondal; Dilipkumar Pal; Silpi Lipsa Mishra; Souvik Roy
Journal:  Nat Prod Commun       Date:  2010-08       Impact factor: 0.986

7.  Comparison of high-speed counter-current chromatography instruments for the separation of the extracts of the seeds of Oroxylum indicum.

Authors:  L J Chen; H Song; X Q Lan; D E Games; I A Sutherland
Journal:  J Chromatogr A       Date:  2005-01-21       Impact factor: 4.759

8.  Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: synthesis, SAR analysis, and biological activity.

Authors:  Shixuan Zhang; Jigang Ma; Yongming Bao; Puwen Yang; Liang Zou; Kangjian Li; Xiaodan Sun
Journal:  Bioorg Med Chem       Date:  2008-07-03       Impact factor: 3.641

Review 9.  Flavonoids, a class of natural products of high pharmacological potency.

Authors:  B Havsteen
Journal:  Biochem Pharmacol       Date:  1983-04-01       Impact factor: 5.858

10.  Molecular modeling reveals the novel inhibition mechanism and binding mode of three natural compounds to staphylococcal α-hemolysin.

Authors:  Jiazhang Qiu; Dacheng Wang; Yu Zhang; Jing Dong; Jianfeng Wang; Xiaodi Niu
Journal:  PLoS One       Date:  2013-11-27       Impact factor: 3.240
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  4 in total

Review 1.  Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents.

Authors:  Haijun Chen; Yu Gao; Ailan Wang; Xiaobin Zhou; Yunquan Zheng; Jia Zhou
Journal:  Eur J Med Chem       Date:  2015-01-16       Impact factor: 6.514

2.  Synthesis of surface nano-molecularly imprinted polymers for sensitive baicalin detection from biological samples.

Authors:  Xiaoli Gu; Hongliang He; Chong-Zhi Wang; Yankun Gao; Hongjuan Zhang; Junli Hong; Shuhu Du; Lina Chen; Chun-Su Yuan
Journal:  RSC Adv       Date:  2015-01-01       Impact factor: 3.361

3.  Ethnopharmacological Inspections of Organic Extract of Oroxylum indicum in Rat Models: A Promising Natural Gift.

Authors:  Mst Marium Begum; Azharul Islam; Rayhana Begum; Md Sahab Uddin; Md Sohanur Rahman; Sumiya Alam; Wahida Akter; Munny Das; Md Sohanur Rahman; A H M Rahmatullah Imon
Journal:  Evid Based Complement Alternat Med       Date:  2019-04-03       Impact factor: 2.629

4.  Flavone-Rich Fractions and Extracts from Oroxylum indicum and Their Antibacterial Activities against Clinically Isolated Zoonotic Bacteria and Free Radical Scavenging Effects.

Authors:  Patchima Sithisarn; Piyanuch Rojsanga; Pongtip Sithisarn
Journal:  Molecules       Date:  2021-03-22       Impact factor: 4.411
  4 in total

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