Literature DB >> 2543130

Analysis of the roles of bluetongue virus outer capsid proteins VP2 and VP5 in determination of virus serotype.

P P Mertens1, S Pedley, J Cowley, J N Burroughs, A H Corteyn, M H Jeggo, D M Jennings, B M Gorman.   

Abstract

Analyses of reassortant and parental strains of BTV serotypes 3 and 10, in serum neutralization tests, confirmed the major role of outer capsid protein VP2 in determination of virus serotype and its involvement in serum neutralization. However, a reassortant BTV strain (R70), containing protein VP5 derived from BTV 3 and VP2 derived from BTV 10, cross-neutralized with both parental virus strains (BTV 3 and BTV 10). It is concluded that VP5 also plays some part in serotype determination of these virus isolates, as analyzed by serum-neutralization, but its role may be less significant than that of VP2.

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Year:  1989        PMID: 2543130     DOI: 10.1016/0042-6822(89)90447-9

Source DB:  PubMed          Journal:  Virology        ISSN: 0042-6822            Impact factor:   3.616


  36 in total

1.  Isolation, complete genome sequencing, and phylogenetic analysis of the first Chuzan virus in China.

Authors:  Fang Wang; Jun Lin; Jitao Chang; Yingying Cao; Shaomin Qin; Jianmin Wu; Li Yu
Journal:  Virus Genes       Date:  2016-01-29       Impact factor: 2.332

2.  Heterologous expression of Bluetongue VP2 viral protein fragment in Pichia pastoris.

Authors:  T N Athmaram; Geetha Bali; Goon G Kahng; Sulatha Dwarakanath
Journal:  Virus Genes       Date:  2007-01-26       Impact factor: 2.332

3.  A protective bivalent vaccine against Rift Valley fever and bluetongue.

Authors:  Eva Calvo-Pinilla; Alejandro Marín-López; Sandra Moreno; Gema Lorenzo; Sergio Utrilla-Trigo; Luis Jiménez-Cabello; Julio Benavides; Aitor Nogales; Rafael Blasco; Alejandro Brun; Javier Ortego
Journal:  NPJ Vaccines       Date:  2020-07-30       Impact factor: 7.344

4.  The evolutionary dynamics of bluetongue virus.

Authors:  Giovanna Carpi; Edward C Holmes; Andrew Kitchen
Journal:  J Mol Evol       Date:  2010-06-05       Impact factor: 2.395

5.  Isolation and Characterization of Bluetongue Virus Recovered from Blood Samples by Immunoaffinity Purification.

Authors:  Karam Chand; Sanchay K Biswas; Bimalendu Mondal
Journal:  Indian J Microbiol       Date:  2018-05-08       Impact factor: 2.461

6.  Growth of a neuroinvasive strain of bluetongue virus in suckling mice.

Authors:  M A Carr; A W Brewer; B I Osburn
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

7.  Association of bluetongue virus gene segment 5 with neuroinvasiveness.

Authors:  M A Carr; C C de Mattos; C A de Mattos; B I Osburn
Journal:  J Virol       Date:  1994-02       Impact factor: 5.103

8.  Full genome characterisation of bluetongue virus serotype 6 from the Netherlands 2008 and comparison to other field and vaccine strains.

Authors:  Sushila Maan; Narender S Maan; Piet A van Rijn; René G P van Gennip; Anna Sanders; Isabel M Wright; Carrie Batten; Bernd Hoffmann; Michael Eschbaumer; Chris A L Oura; Abraham C Potgieter; Kyriaki Nomikou; Peter P C Mertens
Journal:  PLoS One       Date:  2010-04-23       Impact factor: 3.240

9.  RT-PCR assays for seven serotypes of epizootic haemorrhagic disease virus & their use to type strains from the Mediterranean region and North America.

Authors:  Narender S Maan; Sushila Maan; Kyriaki Nomikou; Donna J Johnson; Mehdi El Harrak; Hafsa Madani; Hagai Yadin; Serife Incoglu; Kadir Yesilbag; Andrew B Allison; David E Stallknecht; Carrie Batten; Simon J Anthony; Peter P C Mertens
Journal:  PLoS One       Date:  2010-09-17       Impact factor: 3.240

Review 10.  Adaptive strategies of African horse sickness virus to facilitate vector transmission.

Authors:  Anthony Wilson; Philip Scott Mellor; Camille Szmaragd; Peter Paul Clement Mertens
Journal:  Vet Res       Date:  2008-12-19       Impact factor: 3.683

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