| Literature DB >> 25431250 |
Iuliia Myrgorodska1, Cornelia Meinert, Zita Martins, Louis Le Sergeant d'Hendecourt, Uwe J Meierhenrich.
Abstract
Life, as it is known to us, uses exclusively L-amino acid and D-sugar enantiomers for the molecular architecture of proteins and nucleic acids. This Minireview explores current models of the original symmetry-breaking influence that led to the exogenic delivery to Earth of prebiotic molecules with a slight enantiomeric excess. We provide a short overview of enantiomeric enhancements detected in bodies of extraterrestrial origin, such as meteorites, and interstellar ices simulated in the laboratory. Data are interpreted from different points of view, namely, photochirogenesis, parity violation in the weak nuclear interaction, and enantioenrichment through phase transitions. Photochemically induced enantiomeric imbalances are discussed more specifically in the topical context of the "chirality module" on board the cometary Rosetta spacecraft of the ESA. This device will perform the first enantioselective in situ analyses of samples taken from a cometary nucleus.Entities:
Keywords: Rosetta mission; chirality; circularly polarized light; mirror-symmetry breaking; origin of life
Year: 2014 PMID: 25431250 DOI: 10.1002/anie.201409354
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336