Literature DB >> 25430675

A bacterial mutant library as a tool to study the attack of a defensin peptide.

Simone Moser1, Haritha R Chileveru, Jill Tomaras, Elizabeth M Nolan.   

Abstract

Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli strains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Keio Collection; human defensins; innate immunity; knockout mutants; lipopolysaccharide

Mesh:

Substances:

Year:  2014        PMID: 25430675      PMCID: PMC4341900          DOI: 10.1002/cbic.201402354

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


  35 in total

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