Literature DB >> 25429359

Improving chemoradiotherapy with nanoparticle therapeutics.

Michael Joseph Eblan1, Andrew Zhuang Wang1.   

Abstract

Chemoradiotherapy has been a key treatment paradigm in cancer management. One of the main research objectives in cancer research has been to identify agents and strategies to improve the therapeutic index of chemoradiation. Recent development of nanoparticle (NP)-based chemotherapeutics offers a unique opportunity to improve the delivery of chemotherapy, which can in turn improve chemoradiotherapy's efficacy while lowering toxicity. NP-based chemotherapeutics also possess several characteristics that are well suited for chemoradiotherapy. Therefore, NP chemotherapeutics hold high potential in improving the therapeutic index of chemoradiotherapy. This manuscript reviews the NP properties that are favorable for chemoradiation and the rationale to utilize nanotherapeutics in chemoradiation. This review also discusses the preclinical and clinical data on using NP therapeutics in chemoradiotherapy.

Entities:  

Keywords:  Chemoradiation; NP radiosensitizer; nanomedicine; nanoparticle (NP) chemotherapeutics

Year:  2013        PMID: 25429359      PMCID: PMC4242101          DOI: 10.3978/j.issn.2218-676X.2013.08.04

Source DB:  PubMed          Journal:  Transl Cancer Res        ISSN: 2218-676X            Impact factor:   1.241


  71 in total

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3.  Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis.

Authors:  Michael E Werner; Shrirang Karve; Rohit Sukumar; Natalie D Cummings; Jonathan A Copp; Ronald C Chen; Tian Zhang; Andrew Z Wang
Journal:  Biomaterials       Date:  2011-08-16       Impact factor: 12.479

4.  Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile.

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Journal:  Sci Transl Med       Date:  2012-04-04       Impact factor: 17.956

Review 5.  Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats.

Authors:  Michelle Longmire; Peter L Choyke; Hisataka Kobayashi
Journal:  Nanomedicine (Lond)       Date:  2008-10       Impact factor: 5.307

6.  Pegulated liposomal doxorubicin and cisplatin given concurrently with conventional radiotherapy: a phase I dose-escalation trial for patients with squamous cell carcinoma of head and neck and lung.

Authors:  H Varveris; S Kachris; M Mazonakis; E Lyraraki; A Markouizou; S Karabekios; A Tzedakis; K Perisinakis; J Damilakis; M Vlachaki
Journal:  Oncol Rep       Date:  2004-08       Impact factor: 3.906

7.  Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer.

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Journal:  Ann Oncol       Date:  2004-03       Impact factor: 32.976

8.  Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial.

Authors:  Jaffer A Ajani; Kathryn A Winter; Leonard L Gunderson; John Pedersen; Al B Benson; Charles R Thomas; Robert J Mayer; Michael G Haddock; Tyvin A Rich; Christopher Willett
Journal:  JAMA       Date:  2008-04-23       Impact factor: 56.272

9.  Polymeric nanoparticles containing taxanes enhance chemoradiotherapeutic efficacy in non-small cell lung cancer.

Authors:  Joohee Jung; Sung-Jin Park; Hye Kyung Chung; Hye-Won Kang; Sa-Won Lee; Min Hyo Seo; Heon Joo Park; Si Yeol Song; Seong-Yun Jeong; Eun Kyung Choi
Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-07-14       Impact factor: 7.038

10.  Cetuximab: its unique place in head and neck cancer treatment.

Authors:  Pol Specenier; Jan B Vermorken
Journal:  Biologics       Date:  2013-04-15
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  13 in total

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Review 2.  Capacity of gold nanoparticles in cancer radiotherapy.

Authors:  Nadeem M S Nagi; Yasir A M Khair; Ahmed M E Abdalla
Journal:  Jpn J Radiol       Date:  2017-08-09       Impact factor: 2.374

3.  Rethinking cancer nanotheranostics.

Authors:  Hongmin Chen; Weizhong Zhang; Guizhi Zhu; Jin Xie; Xiaoyuan Chen
Journal:  Nat Rev Mater       Date:  2017-05-09       Impact factor: 66.308

Review 4.  Polymer nanostructures synthesized by controlled living polymerization for tumor-targeted drug delivery.

Authors:  Christine E Wang; Patrick S Stayton; Suzie H Pun; Anthony J Convertine
Journal:  J Control Release       Date:  2015-09-02       Impact factor: 9.776

Review 5.  Application of nanotechnology to cancer radiotherapy.

Authors:  Yu Mi; Zhiying Shao; Johnny Vang; Orit Kaidar-Person; Andrew Z Wang
Journal:  Cancer Nanotechnol       Date:  2016-12-19

6.  Long-term tolerance and cardiac function in breast cancer patients receiving trastuzumab therapy.

Authors:  Ping Huang; Shujun Dai; Zhimin Ye; Yajuan Liu; Zhanhong Chen; Yabing Zheng; Xiying Shao; Lei Lei; Xiaojia Wang
Journal:  Oncotarget       Date:  2017-01-10

Review 7.  Evolving role of biomaterials in diagnostic and therapeutic radiation oncology.

Authors:  Siyu Shi; Ravi Vissapragada; Joseph Abi Jaoude; Caroline Huang; Anmol Mittal; Elisa Liu; Jim Zhong; Vivek Kumar
Journal:  Bioact Mater       Date:  2020-02-21

8.  Radiosensitization Effects by Bismuth Oxide Nanoparticles in Combination with Cisplatin for High Dose Rate Brachytherapy.

Authors:  Noor Nabilah Talik Sisin; Khairunisak Abdul Razak; Safri Zainal Abidin; Nor Fazila Che Mat; Reduan Abdullah; Raizulnasuha Ab Rashid; Muhammad Afiq Khairil Anuar; Nur Hamizah Mohd Zainudin; Nashrulhaq Tagiling; Norazlina Mat Nawi; Wan Nordiana Rahman
Journal:  Int J Nanomedicine       Date:  2019-12-18

9.  EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

Authors:  Lei Song; Nadia Falzone; Katherine A Vallis
Journal:  Int J Radiat Biol       Date:  2016-03-21       Impact factor: 2.694

Review 10.  Nanotechnology for Cancer Therapy Based on Chemotherapy.

Authors:  Chen-Yang Zhao; Rui Cheng; Zhe Yang; Zhong-Min Tian
Journal:  Molecules       Date:  2018-04-04       Impact factor: 4.411

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