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Literature DB >> 25428669

Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review.

Ljiljana Serman¹, Tamara Nikuseva Martic, Alan Serman, Semir Vranic.

Abstract

Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.

Entities: Disease

Mesh：

Year: 2014 PMID： 25428669 PMCID： PMC4333971 DOI： 10.17305/bjbms.2014.4.205

Source DB: PubMed Journal: Bosn J Basic Med Sci ISSN： 1512-8601 Impact factor: 3.363

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