Moutaz Takriti1, Mayssoon Dashash. 1. Department of Paediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syria.
Abstract
AIM: To investigate cephalometric craniofacial parameters (skeletal and dental) of β-thalassemic-major patients and to compare findings with a group of healthy patients in the same age group. METHODS: Fifty-one Syrian thalassemic-major patients aged 8-12 years were recruited. Lateral cephalometric radiographs were taken. Linear and angular cephalometric measurements were recorded and compared with Syrian controls (n=50) in the same age group. RESULTS: Thalassemic patients, when compared with controls, showed significant retrognathia in the mandible (reduced sella [mid-point of sella turcica]-nasion [most anterior point on the frontonasal suture] B-point [deepest point on the concavity of the mandibular profile between the alveolar crest and the point of the chin] angle, and decreased sella-nasion-pogonion [most anterior point on the bony chin] angle, P<0.0001), a significant decrease in ramus height (articulare-gonian=36.51 ± 3.87 mm, P<0.0001). They also exhibited a significant class II skeletal pattern (P<0.0001) and a convex facial profile as the nasion A-point (deepest point on maxillary profile between the anterior nasal spine and the alveolar crest) pogonion angle and maxillomandibular A-point-nasion P-point angle increased. They also showed a highly-significant decrease in the total posterior facial height (sella gonion [most posterior, inferior point on the angle of the mandible]=64.24 ± 5.73 mm, P<0.0001) and significant increase in the total anterior facial height (N-Me = 110.78 ± 6.66 mm, P=0.009) when compared to controls. CONCLUSION: Thalassemic patients exhibited a skeletal class II malocclusion, retrognathia of the mandible, a short height of the ramus, an increase in anterior facial height, and a decrease in posterior facial height.
AIM: To investigate cephalometric craniofacial parameters (skeletal and dental) of β-thalassemic-major patients and to compare findings with a group of healthy patients in the same age group. METHODS: Fifty-one Syrian thalassemic-major patients aged 8-12 years were recruited. Lateral cephalometric radiographs were taken. Linear and angular cephalometric measurements were recorded and compared with Syrian controls (n=50) in the same age group. RESULTS: Thalassemic patients, when compared with controls, showed significant retrognathia in the mandible (reduced sella [mid-point of sella turcica]-nasion [most anterior point on the frontonasal suture] B-point [deepest point on the concavity of the mandibular profile between the alveolar crest and the point of the chin] angle, and decreased sella-nasion-pogonion [most anterior point on the bony chin] angle, P<0.0001), a significant decrease in ramus height (articulare-gonian=36.51 ± 3.87 mm, P<0.0001). They also exhibited a significant class II skeletal pattern (P<0.0001) and a convex facial profile as the nasion A-point (deepest point on maxillary profile between the anterior nasal spine and the alveolar crest) pogonion angle and maxillomandibular A-point-nasion P-point angle increased. They also showed a highly-significant decrease in the total posterior facial height (sella gonion [most posterior, inferior point on the angle of the mandible]=64.24 ± 5.73 mm, P<0.0001) and significant increase in the total anterior facial height (N-Me = 110.78 ± 6.66 mm, P=0.009) when compared to controls. CONCLUSION: Thalassemic patients exhibited a skeletal class II malocclusion, retrognathia of the mandible, a short height of the ramus, an increase in anterior facial height, and a decrease in posterior facial height.