Literature DB >> 25426239

Anti-NMDA encephalitis: an uncommon, autoimmune mediated form of encephalitis.

Avetis Azizyan1, Joshua R Albrektson1, Marcel M Maya1, Barry D Pressman1, Franklin Moser1.   

Abstract

We report an interesting case of a 19 year old female with findings on MRI suggestive of viral encephalitis. An extensive workup was negative for infectious causes and she was subsequently diagnosed with anti-NMDA encephalitis. Anti-NMDA encephalitis is a highly lethal but treatable form of autoimmune encephalitis that has recently been characterized. It is frequently found in young women and associated with an underlying teratoma. Although rare, this diagnosis should be considered in young females for whom a rapid onset of encephalitis cannot be explained by more common causes.

Entities:  

Keywords:  Anti-NMDA; MRI; NMDA receptor; encephalitis; teratoma

Mesh:

Substances:

Year:  2014        PMID: 25426239      PMCID: PMC4242142          DOI: 10.3941/jrcr.v8i8.1566

Source DB:  PubMed          Journal:  J Radiol Case Rep        ISSN: 1943-0922


  12 in total

1.  Reversible limbic encephalitis caused by ovarian teratoma.

Authors:  K Nokura; H Yamamoto; Y Okawara; H Koga; H Osawa; K Sakai
Journal:  Acta Neurol Scand       Date:  1997-06       Impact factor: 3.209

2.  Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis.

Authors:  Ethan G Hughes; Xiaoyu Peng; Amy J Gleichman; Meizan Lai; Lei Zhou; Ryan Tsou; Thomas D Parsons; David R Lynch; Josep Dalmau; Rita J Balice-Gordon
Journal:  J Neurosci       Date:  2010-04-28       Impact factor: 6.167

3.  Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab.

Authors:  H Ishiura; S Matsuda; M Higashihara; M Hasegawa; A Hida; R Hanajima; T Yamamoto; J Shimizu; J Dalmau; S Tsuji
Journal:  Neurology       Date:  2008-12-02       Impact factor: 9.910

4.  An acutely confused 15-year-old girl.

Authors:  H Okamura; N Oomori; Y Uchitomi
Journal:  Lancet       Date:  1997-08-16       Impact factor: 79.321

5.  Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma.

Authors:  Roberta Vitaliani; Warren Mason; Beau Ances; Theodore Zwerdling; Zhilong Jiang; Josep Dalmau
Journal:  Ann Neurol       Date:  2005-10       Impact factor: 10.422

6.  Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma.

Authors:  Josep Dalmau; Erdem Tüzün; Hai-yan Wu; Jaime Masjuan; Jeffrey E Rossi; Alfredo Voloschin; Joachim M Baehring; Haruo Shimazaki; Reiji Koide; Dale King; Warren Mason; Lauren H Sansing; Marc A Dichter; Myrna R Rosenfeld; David R Lynch
Journal:  Ann Neurol       Date:  2007-01       Impact factor: 10.422

7.  Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.

Authors:  S H Gultekin; M R Rosenfeld; R Voltz; J Eichen; J B Posner; J Dalmau
Journal:  Brain       Date:  2000-07       Impact factor: 13.501

8.  Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies.

Authors:  Josep Dalmau; Amy J Gleichman; Ethan G Hughes; Jeffrey E Rossi; Xiaoyu Peng; Meizan Lai; Scott K Dessain; Myrna R Rosenfeld; Rita Balice-Gordon; David R Lynch
Journal:  Lancet Neurol       Date:  2008-10-11       Impact factor: 44.182

9.  Neurological response to early removal of ovarian teratoma in anti-NMDAR encephalitis.

Authors:  M Seki; S Suzuki; T Iizuka; T Shimizu; Y Nihei; N Suzuki; J Dalmau
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-11-21       Impact factor: 10.154

10.  Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma.

Authors:  Erdem Tüzün; Lei Zhou; Joachim M Baehring; Serguei Bannykh; Myrna R Rosenfeld; Josep Dalmau
Journal:  Acta Neuropathol       Date:  2009-12       Impact factor: 17.088

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  6 in total

1.  Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females.

Authors:  Kamlesh Kumari; Neeru Sahni; Vimla Kumari; Vikas Saini
Journal:  Turk J Anaesthesiol Reanim       Date:  2017-09-15

Review 2.  Magnetic resonance imaging and magnetic resonance spectroscopy in a young male patient with anti-N-methyl-D-aspartate receptor encephalitis and uncommon cerebellar involvement: A case report with review of the literature.

Authors:  Alessandra Splendiani; Valentina Felli; Alessandra Di Sibio; Antonio Gennarelli; Lucia Patriarca; Paolo Stratta; Ernesto Di Cesare; Alessandro Rossi; Gallucci Massimo
Journal:  Neuroradiol J       Date:  2015-11-27

3.  Anaesthetic management of a patient with anti-NMDA receptor encephalitis.

Authors:  Mohammed Aslam Shaikh; Tasneem Dhansura; Shweta Gandhi; Tarana Shaikh
Journal:  Indian J Anaesth       Date:  2015-04

4.  Anti-N-methyl-D-aspartate receptor encephalitis with an imaging-invisible ovarian teratoma: a case report.

Authors:  Zainab M Abdul-Rahman; Peter K Panegyres; Margareta Roeck; David Hawkins; Jude Bharath; Paul Grolman; Cliffe Neppe; David Palmer
Journal:  J Med Case Rep       Date:  2016-10-24

5.  Brain paraneoplastic syndromes in a patient with mediastinal ganglioneuroma.

Authors:  Jose Migue Escudero-Fernandez; Angel Sánchez-Montañez Garcia-Carpintero; Ignacio Delgado-Alvarez; Amparo Castellote-Alonso; Elida Josefa Vázquez-Mendez
Journal:  Radiol Case Rep       Date:  2020-09-02

6.  A refractory anti-NMDA receptor encephalitis successfully treated by bilateral salpingo-oophorectomy and intrathecal injection of methotrexate and dexamethasone: a case report.

Authors:  Dongmei Wang; Yongming Wu; Zhong Ji; Shengnan Wang; Yunqi Xu; Kaibin Huang; Yu Peng; Hui Zheng; Honghao Wang; Xiaomei Zhang; Suyue Pan
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671

  6 in total

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