Literature DB >> 25426220

Duplicated pelvic floor musculature and diastematomyelia in a cloacal exstrophy patient.

Brian M Inouye1, Ali Tourchi1, Eric Z Massanyi2, John P Gearhart1, Aylin Tekes3.   

Abstract

Cloacal exstrophy is the most severe and rare form of the exstrophy-epispadias complex, presenting with exposed bladder halves extruding through an abdominal wall defect and variable genitourinary, gastrointestinal, musculoskeletal, and neurological defects. The authors report magnetic resonance imaging findings of a neurologically-intact, 24-month-old female with cloacal exstrophy who presented with anterior spinal dysraphism and diastematomyelia and duplicate pelvic floor musculature. The constellation of defects suggests a common genetic, biochemical, and embryological origin for duplication of the bladder, spinal cord, and pelvic floor muscles occurring in the fourth week of gestation.

Entities:  

Keywords:  Cloacal Exstrophy; Diastematomyelia; Duplicated Pelvic Floor; Etiology; Exstrophy-Epispadias Complex; Spinal Dysraphism

Mesh:

Year:  2014        PMID: 25426220      PMCID: PMC4242151          DOI: 10.3941/jrcr.v8i10.2088

Source DB:  PubMed          Journal:  J Radiol Case Rep        ISSN: 1943-0922


  13 in total

1.  [Dorso-ventral gradient of maturation for puborectalis muscle].

Authors:  H Copin; D Bourdelat; J P Barbet
Journal:  Morphologie       Date:  1999-09

2.  Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling.

Authors:  Ryuma Haraguchi; Jun Motoyama; Hiroshi Sasaki; Yoshihiko Satoh; Shinichi Miyagawa; Naomi Nakagata; Anne Moon; Gen Yamada
Journal:  Development       Date:  2007-01-03       Impact factor: 6.868

Review 3.  Modern management of bladder exstrophy repair.

Authors:  Brian M Inouye; Eric Z Massanyi; Heather Di Carlo; Bhavik B Shah; John P Gearhart
Journal:  Curr Urol Rep       Date:  2013-08       Impact factor: 3.092

4.  Optimal management of cloacal exstrophy.

Authors:  C Howell; A Caldamone; H Snyder; M Ziegler; J Duckett
Journal:  J Pediatr Surg       Date:  1983-08       Impact factor: 2.545

5.  Exstrophy of the cloaca and exstrophy of the bladder: two different expressions of a primary developmental field defect.

Authors:  M L Martínez-Frías; E Bermejo; E Rodríguez-Pinilla; J L Frías
Journal:  Am J Med Genet       Date:  2001-04-01

6.  Genome-wide expression profiling of urinary bladder implicates desmosomal and cytoskeletal dysregulation in the bladder exstrophy-epispadias complex.

Authors:  Lihong Qi; Kun Chen; David J Hur; Garima Yagnik; Yegappan Lakshmanan; Lori E Kotch; Gerald H Ashrafi; Francisco Martinez-Murillo; Jeanne Kowalski; Cyrill Naydenov; Lars Wittler; John P Gearhart; Markus Draaken; Heiko Reutter; Michael Ludwig; Simeon A Boyadjiev
Journal:  Int J Mol Med       Date:  2011-03-22       Impact factor: 4.101

7.  Failed exstrophy closure: management and outcome.

Authors:  Thomas E Novak; John P Costello; Ryan Orosco; Paul D Sponseller; Erin Mack; John P Gearhart
Journal:  J Pediatr Urol       Date:  2009-11-10       Impact factor: 1.830

8.  A previously unreported variant of exstrophy cloaca.

Authors:  Arbay O Ciftçi; Tutku Soyer; F Cahit Tanyel
Journal:  Turk J Pediatr       Date:  2008 Nov-Dec       Impact factor: 0.552

9.  Cloacal exstrophy: experience with 20 cases.

Authors:  D P Lund; W H Hendren
Journal:  J Pediatr Surg       Date:  1993-10       Impact factor: 2.545

Review 10.  Modern management of the exstrophy-epispadias complex.

Authors:  Brian M Inouye; Ali Tourchi; Heather N Di Carlo; Ezekiel E Young; John P Gearhart
Journal:  Surg Res Pract       Date:  2014-01-05
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