| Literature DB >> 25424819 |
Ahmed Zaïem1, Senda El Ferjani, Ghozlane Lakhoua, Rym Sahnoun, Talel Badri, Sarrah Kastalli, Riadh Daghfous, Mohamed Lakhal, Sihem El Aidli.
Abstract
The disseminated BCG infection is a rare and serious complication of bacillus Calmette-Guerin (BCG) vaccine. We report a case of probable disseminated BCG infection in a 10-month-old child who had been vaccinated by BCG vaccine at birth. No incident was noted on the first days of vaccination. At the age of 40 days, she developed left supra clavicular and axillar abcessed lymph nodes. She was treated by surgical flattening of the lymph adenopathy. The same lymph node recurred at the age of 6 months and was treated with surgery. Few weeks after the second episode, cutaneous ulcerative lesions appeared. Cutaneous biopsy was performed and showed lesions compatible with tuberculosis. X-rays showed osteolysis of P1 of the middle finger in the left hand. She was treated by anti-tuberculosis antibiotics.Entities:
Keywords: BCG vaccine; adverse effect following immunization; disseminated infection
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Year: 2014 PMID: 25424819 PMCID: PMC4186025 DOI: 10.4161/hv.28913
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN: 2164-5515 Impact factor: 3.452