Literature DB >> 25423915

Large-pore ultrasmall mesoporous organosilica nanoparticles: micelle/precursor co-templating assembly and nuclear-targeted gene delivery.

Meiying Wu1, Qingshuo Meng, Yu Chen, Yanyan Du, Lingxia Zhang, Yaping Li, Linlin Zhang, Jianlin Shi.   

Abstract

A novel micelle/precursor co-templating assembly strategy is successfully developed to synthesize large-pore ultrasmall mesoporous organosilica nanoparticles (MONs). Furthermore, elaborately designed MONs with a cell-penetrating peptide (TAT) (MONs-PTAT) are constructed for highly efficient intranuclear gene delivery. They exhibit a high loading capacity, improved protection for the loaded gene, and enhanced transfection efficiencies of EGFP plasmid (pEGFP).
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  gene delivery; large mesopores; mesoporous organosilicas; nuclear-targeted

Mesh：

Substances：

Year:  2014        PMID： 25423915     DOI： 10.1002/adma.201404256

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  24 in total

1.  Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy.

Authors:  Berrin Küçüktürkmen; Jessica M Rosenholm
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Acidity/Reducibility Dual-Responsive Hollow Mesoporous Organosilica Nanoplatforms for Tumor-Specific Self-Assembly and Synergistic Therapy.

Authors:  Wei Tang; Wenpei Fan; Zhantong Wang; Weizhong Zhang; Shiyi Zhou; Yijing Liu; Zhen Yang; Emily Shao; Guofeng Zhang; Orit Jacobson; Lingling Shan; Rui Tian; Siyuan Cheng; Lisen Lin; Yulun Dai; Zheyu Shen; Gang Niu; Jin Xie; Xiaoyuan Chen
Journal:  ACS Nano       Date:  2018-11-15       Impact factor: 15.881

Review 3.  Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

Authors:  María Vallet-Regí; Ferdi Schüth; Daniel Lozano; Montserrat Colilla; Miguel Manzano
Journal:  Chem Soc Rev       Date:  2022-07-04       Impact factor: 60.615

4.  Ultrasmall Porous Silica Nanoparticles with Enhanced Pharmacokinetics for Cancer Theranostics.

Authors:  Carolina A Ferreira; Shreya Goel; Emily B Ehlerding; Zachary T Rosenkrans; Dawei Jiang; Tuanwei Sun; Eduardo Aluicio-Sarduy; Jonathan W Engle; Dalong Ni; Weibo Cai
Journal:  Nano Lett       Date:  2021-05-24       Impact factor: 12.262

Review 5.  Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications.

Authors:  Bazla Siddiqui; Asim Ur Rehman; Ihsan-Ul Haq; Amal A Al-Dossary; Abdelhamid Elaissari; Naveed Ahmed
Journal:  Int J Pharm X       Date:  2022-04-19

Review 6.  Mesoporous Silica Nanoparticles as Drug Delivery Vehicles in Cancer.

Authors:  Anna Watermann; Juergen Brieger
Journal:  Nanomaterials (Basel)       Date:  2017-07-22       Impact factor: 5.076

7.  Enhanced Blood Suspensibility and Laser-Activated Tumor-specific Drug Release of Theranostic Mesoporous Silica Nanoparticles by Functionalizing with Erythrocyte Membranes.

Authors:  Jinghan Su; Huiping Sun; Qingshuo Meng; Pengcheng Zhang; Qi Yin; Yaping Li
Journal:  Theranostics       Date:  2017-01-07       Impact factor: 11.556

8.  Biodegradable Periodic Mesoporous Organosilica (BPMO) Loaded with Daunorubicin: A Promising Nanoparticle-Based Anticancer Drug.

Authors:  Ngoc Xuan Dat Mai; Albane Birault; Kotaro Matsumoto; Hanh Kieu Thi Ta; Soontaree Grace Intasa-Ard; Kendall Morrison; Phan Bach Thang; Tan Le Hoang Doan; Fuyuhiko Tamanoi
Journal:  ChemMedChem       Date:  2020-02-11       Impact factor: 3.466

9.  Biodegradable and Renal Clearable Inorganic Nanoparticles.

Authors:  Emily B Ehlerding; Feng Chen; Weibo Cai
Journal:  Adv Sci (Weinh)       Date:  2015-10-27       Impact factor: 16.806

10.  Coordination-Responsive Longitudinal Relaxation Tuning as a Versatile MRI Sensing Protocol for Malignancy Targets.

Authors:  Kun Zhang; Yu Cheng; Weiwei Ren; Liping Sun; Chang Liu; Dan Wang; Lehang Guo; Huixiong Xu; Yongxiang Zhao
Journal:  Adv Sci (Weinh)       Date:  2018-07-10       Impact factor: 16.806
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