Wan-Ting Huang1, Chih-Hsi Chang2, Yu-Fen Hsu2, Jen-Hsiang Chuang3. 1. Taiwan Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan muagi@cdc.gov.tw. 2. Taiwan Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan. 3. Taiwan Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan Institute of Biomedical Informatics & Institute of Public Health, National Yang-Ming University, Taipei, Taiwan.
Abstract
BACKGROUND: This study aims to assess factors associated with fatal hospitalized influenza with complications in Taiwan. METHODS: We identified reports of complications and illness onset in patients hospitalized with influenza between week 26, 2009 and week 25, 2012 from the National Notifiable Disease Surveillance System. We used a multivariate logistic regression model to evaluate covariates that can be associated with in-hospital mortality. RESULTS: Among 4735 patients (413 deaths), age ≥50 years (p<0.001), male (p=0.014), comorbidities (p<0.001), and delayed oseltamivir treatment (p<0.001) increased the likelihood of in-hospital mortality. CONCLUSIONS: We recommend influenza vaccination and early antiviral treatment for at-risk populations.
BACKGROUND: This study aims to assess factors associated with fatal hospitalized influenza with complications in Taiwan. METHODS: We identified reports of complications and illness onset in patients hospitalized with influenza between week 26, 2009 and week 25, 2012 from the National Notifiable Disease Surveillance System. We used a multivariate logistic regression model to evaluate covariates that can be associated with in-hospital mortality. RESULTS: Among 4735 patients (413 deaths), age ≥50 years (p<0.001), male (p=0.014), comorbidities (p<0.001), and delayed oseltamivir treatment (p<0.001) increased the likelihood of in-hospital mortality. CONCLUSIONS: We recommend influenza vaccination and early antiviral treatment for at-risk populations.
Authors: Laura M Vos; Jan Jelrik Oosterheert; Andy I M Hoepelman; Louis J Bont; Frank E J Coenjaerts; Christiana A Naaktgeboren Journal: J Med Virol Date: 2019-08-28 Impact factor: 2.327