Literature DB >> 25421692

Epigenetics of gastric cancer.

Mingzhou Guo1, Wenji Yan.   

Abstract

Epigenetic changes frequently occur in human gastric cancer. Gene promoter region hypermethylation, genomic global hypomethylation, histone modifications, and alterations of noncoding RNAs are major epigenetic changes in gastric cancer. As a key risk factor of gastric cancer, H. pylori infection is an independent predictive indicator of gene methylation. A growing number of epigenetic studies in gastric cancer have provided lots of potential diagnostic and prognostic markers and therapeutic targets.

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Year:  2015        PMID： 25421692     DOI： 10.1007/978-1-4939-1804-1_41

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

1.  PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3β/β-Catenin Signaling Pathway in Human Gastric Cancer.

Authors:  Jingjing Ma; Xufeng Guo; Jixiang Zhang; Dandan Wu; Xue Hu; Jiao Li; Qingzhi Lan; Ya Liu; Weiguo Dong
Journal:  Dig Dis Sci       Date:  2017-10-13       Impact factor: 3.199

2.  [Screening of early gastric cancer using Pre-Activation Squeeze-and-Excitation ResNet].

Authors:  X Zhang; Y Wang; J Zhang; H Sun; D Wang; Y Chen; Z Zhou
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2021-11-20

3.  Microrna-136 promotes proliferation and invasion ingastric cancer cells through Pten/Akt/P-Akt signaling pathway.

Authors:  Xuyan Chen; Zhiming Huang; Renpin Chen
Journal:  Oncol Lett       Date:  2018-01-24       Impact factor: 2.967

4.  Relationship between DLEC1 and PBX3 promoter methylation and the risk and prognosis of gastric cancer in peripheral blood leukocytes.

Authors:  Wenzhen Xie; Haibo Zhou; Qian Han; Tong Sun; Chuang Nie; Jia Hong; Rongrong Wei; Anastasiia Leonteva; Xu Han; Jing Wang; Xinyu Du; Lin Zhu; Yashuang Zhao; Wenjing Tian; Yingwei Xue
Journal:  J Cancer Res Clin Oncol       Date:  2020-03-06       Impact factor: 4.553

5.  Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer.

Authors:  Yan Jia; Baoping Cao; Yunsheng Yang; Enqiang Linghu; Qimin Zhan; Youyong Lu; Yingyan Yu; James G Herman; Mingzhou Guo
Journal:  Oncotarget       Date:  2015-10-20

6.  Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer.

Authors:  Nadia Ferlazzo; Monica Currò; Angelo Zinellu; Daniela Caccamo; Gaetano Isola; Valeria Ventura; Ciriaco Carru; Giovanni Matarese; Riccardo Ientile
Journal:  Int J Mol Sci       Date:  2017-03-29       Impact factor: 5.923

Review 7.  Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets.

Authors:  Cameron Lindsay; Hadi Seikaly; Vincent L Biron
Journal:  J Otolaryngol Head Neck Surg       Date:  2017-01-31

Review 8.  The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinoma.

Authors:  Kai Ma; Baoping Cao; Mingzhou Guo
Journal:  Clin Epigenetics       Date:  2016-04-22       Impact factor: 6.551

9.  MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression.

Authors:  Chang Li; Lei Song; Zhuo Zhang; Xiao-Xue Bai; Ming-Fu Cui; Lian-Jun Ma
Journal:  Oncotarget       Date:  2016-10-11

Review 10.  Epigenetic regulation of long non-coding RNAs in gastric cancer.

Authors:  Zhixia Zhou; Zhijuan Lin; Xin Pang; Muhammad Akram Tariq; Xiang Ao; Peifeng Li; Jianxun Wang
Journal:  Oncotarget       Date:  2017-12-16
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