Literature DB >> 25421683

Promoter hypermethylation as a biomarker in prostate adenocarcinoma.

Jong Y Park1.   

Abstract

There is increasing evidence that DNA methylation is a critical source of gene regulation. In addition, interindividual differences in DNA methylation status in cancer related genes are associated with risk and progression of prostate cancer. Therefore, DNA methylation in cancer related genes can be potential biomarkers and therapeutic targets for prostate cancer.In this chapter, current information on frequently hypermethylated genes associated with the carcinogenesis and progression of prostate cancer was updated. The potential biological role of hypermethylated genes in prostate cancer is discussed. These findings may provide new information of the pathogenesis, the exciting potential to be predictive and to provide strategies for personalized treatment of prostate cancer.

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Year:  2015        PMID： 25421683     DOI： 10.1007/978-1-4939-1804-1_32

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  9 in total

1.  Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels.

Authors:  Christa Haldrup; Anne-Sofie Lynnerup; Tine Maj Storebjerg; Søren Vang; Peter Wild; Tapio Visakorpi; Christian Arsov; Wolfgang A Schulz; Johan Lindberg; Henrik Grönberg; Lars Egevad; Michael Borre; Torben Falck Ørntoft; Søren Høyer; Karina Dalsgaard Sørensen
Journal:  Mol Oncol       Date:  2016-02-09       Impact factor: 7.449

2.  Prostate cancer small non-coding RNA transcriptome in Arabs.

Authors:  Jingxuan Shan; Khalid Al-Rumaihi; Karim Chouchane; Issam Al-Bozom; Danny Rabah; Karim Farhat; Lotfi Chouchane
Journal:  J Transl Med       Date:  2017-12-21       Impact factor: 5.531

3.  Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies.

Authors:  Christa Haldrup; Anne L Pedersen; Nadia Øgaard; Siri H Strand; Søren Høyer; Michael Borre; Torben F Ørntoft; Karina D Sørensen
Journal:  Mol Oncol       Date:  2018-03-13       Impact factor: 6.603

4.  Comprehensive Evaluation of TFF3 Promoter Hypomethylation and Molecular Biomarker Potential for Prostate Cancer Diagnosis and Prognosis.

Authors:  Maibritt Nørgaard; Christa Haldrup; Tine Maj Storebjerg; Else Marie Vestergaard; Peter J Wild; Søren Høyer; Michael Borre; Torben Falck Ørntoft; Karina Dalsgaard Sørensen
Journal:  Int J Mol Sci       Date:  2017-09-20       Impact factor: 5.923

5.  Identification of key DNA methylation-driven genes in prostate adenocarcinoma: an integrative analysis of TCGA methylation data.

Authors:  Ning Xu; Yu-Peng Wu; Zhi-Bin Ke; Ying-Chun Liang; Hai Cai; Wen-Ting Su; Xuan Tao; Shao-Hao Chen; Qing-Shui Zheng; Yong Wei; Xue-Yi Xue
Journal:  J Transl Med       Date:  2019-09-18       Impact factor: 5.531

6.  The Impact of Prostate Cancer Upgrading and Upstaging on Biochemical Recurrence and Cancer-Specific Survival.

Authors:  Arnas Bakavičius; Mingailė Drevinskaitė; Kristina Daniūnaitė; Marija Barisienė; Sonata Jarmalaitė; Feliksas Jankevičius
Journal:  Medicina (Kaunas)       Date:  2020-02-04       Impact factor: 2.430

7.  Urinary DNA methylation biomarkers for prediction of prostate cancer upgrading and upstaging.

Authors:  Arnas Bakavicius; Kristina Daniunaite; Kristina Zukauskaite; Marija Barisiene; Sonata Jarmalaite; Feliksas Jankevicius
Journal:  Clin Epigenetics       Date:  2019-08-05       Impact factor: 6.551

8.  Promoter Methylation of PRKCB, ADAMTS12, and NAALAD2 Is Specific to Prostate Cancer and Predicts Biochemical Disease Recurrence.

Authors:  Kristina Daniunaite; Arnas Bakavicius; Kristina Zukauskaite; Ieva Rauluseviciute; Juozas Rimantas Lazutka; Albertas Ulys; Feliksas Jankevicius; Sonata Jarmalaite
Journal:  Int J Mol Sci       Date:  2021-06-05       Impact factor: 5.923

9.  Dysregulation of DNA Methylation and Epigenetic Clocks in Prostate Cancer among Puerto Rican Men.

Authors:  Anders Berglund; Jaime Matta; Jarline Encarnación-Medina; Carmen Ortiz-Sanchéz; Julie Dutil; Raymond Linares; Joshua Marcial; Caren Abreu-Takemura; Natasha Moreno; Ryan Putney; Ratna Chakrabarti; Hui-Yi Lin; Kosj Yamoah; Carlos Diaz Osterman; Liang Wang; Jasreman Dhillon; Youngchul Kim; Seung Joon Kim; Gilberto Ruiz-Deya; Jong Y Park
Journal:  Biomolecules       Date:  2021-12-21
  9 in total

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