Literature DB >> 25419062

Bilateral invasive duct carcinoma, phyllodes tumor and multiple fibroadenomas of breast associated with lymph node metastases - rare coexistence.

Sunila Jain1, Ramneet Kaur2, Rajeev Agarwal3, Prem Chopra2.   

Abstract

Concomitant occurrence of phyllodes tumor with an in situ or invasive carcinoma in the breast is an uncommon phenomenon and has been reported sparingly. We describe a rare case of simultaneous bilateral intraductal and infiltrating duct carcinoma with coexisting fibroadenomas and phyllodes tumor. To the best of our knowledge, only 19 cases of invasive carcinoma with phyllodes tumor have been reported so far and lymph node metastases has been described only once. A 43 year-old woman presented with multiple bilateral breast lumps. Core biopsies revealed phyllodes tumor in the right breast and invasive duct carcinoma of the left breast. Simple mastectomy done for right breast showed foci of invasive carcinoma arising in phyllodes tumor. Metastasis was detected in the left axillary lymph nodes. This case is being reported to create awareness of this rare transformation, which has significant prognostic and therapeutic implications.

Entities:  

Keywords:  Breast; Carcinoma; Invasive; Phyllodes; Tumor

Year:  2014        PMID: 25419062      PMCID: PMC4235864          DOI: 10.1007/s13193-014-0338-z

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  7 in total

1.  Malignant cystosarcoma phyllodes associated with scirrhous carcinoma of the breast: a case report.

Authors:  M V McCormick; S P Pillay
Journal:  S Afr Med J       Date:  1977-11-19

2.  Cystosarcoma phyllodes. A review of 19 cases with emphasis on the occurrence of associated breast carcinoma.

Authors:  L Christensen; M Nielsen; P M Madsen
Journal:  Acta Pathol Microbiol Immunol Scand A       Date:  1986-01

3.  Phyllodes tumors of the breast: the role of pathologic parameters.

Authors:  Puay-Hoon Tan; Thiyagarajan Jayabaskar; Khoon-Leong Chuah; Hwei-Yee Lee; Yen Tan; Maryam Hilmy; Huynh Hung; Sathiyamoorthy Selvarajan; Boon-Huat Bay
Journal:  Am J Clin Pathol       Date:  2005-04       Impact factor: 2.493

4.  Malignant phyllodes tumour with liposarcomatous differentiation, invasive tubular carcinoma, and ductal and lobular carcinoma in situ: case report and review of the literature.

Authors:  Mardiana Abdul Aziz; Frank Sullivan; Michael J Kerin; Grace Callagy
Journal:  Patholog Res Int       Date:  2010-07-05

5.  Malignant phyllodes tumour with intraductal and invasive carcinoma and lymph node metastasis.

Authors:  A Korula; J Varghese; M Thomas; F Vyas; A Korula
Journal:  Singapore Med J       Date:  2008-11       Impact factor: 1.858

6.  Coexistence of benign phyllodes tumor and invasive ductal carcinoma in distinct breasts: case report.

Authors:  Guerino Barbalaco Neto; Claudia Rossetti; Natalia A Souza; Fernando LA Fonseca; Ligia Ajaime Azzalis; Virginia Berlanga Campos Junqueira; Vitor E Valenti; Luiz Carlos de Abreu
Journal:  Eur J Med Res       Date:  2012-04-25       Impact factor: 2.175

7.  In-situ and invasive carcinoma within a phyllodes tumor associated with lymph node metastases.

Authors:  Jeremy R Parfitt; Chris Armstrong; Frances O'malley; Joan Ross; Alan B Tuck
Journal:  World J Surg Oncol       Date:  2004-12-15       Impact factor: 2.754

  7 in total
  3 in total

1.  A Clinicopathological Study of Benign Phyllodes Tumour of Breast with Emphasis on Unusual Features.

Authors:  Kishori Moni Panda; Reena Naik
Journal:  J Clin Diagn Res       Date:  2016-07-01

2.  Malignant Epithelial Transformation in Phyllodes Tumor: A Population-Based Case Series.

Authors:  Ralph L Widya; Myra F Rodrigues; Pauline T Truong; Peter H Watson; Lorna M Weir; Margaret A Knowling; Elaine S Wai
Journal:  Cureus       Date:  2017-11-03

3.  Coexistence of malignant phyllodes tumor and her2-positive locally advanced breast cancer in distinct breasts: A case report.

Authors:  Tomoi Sato; Ichiro Muto; Takeshi Sakai
Journal:  Int J Surg Case Rep       Date:  2016-01-06
  3 in total

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