| Literature DB >> 2541711 |
Abstract
In liposomes with reconstituted shark Na,K-ATPase produced to contain sucrose addition of external Na+ and ATP induce an uncoupled Na+-efflux on inside-out oriented pumps which can be inhibited by digitoxigenin. This flux mode is found to be electrogenic and accompanied by hydrolysis of ATP. The coupling ratio of Nacyt transported per ATP split is 3:1 measured as the initial rate of rise in transmembrane potential and initial rate of liberated Pi.Entities:
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Year: 1989 PMID： 2541711 DOI： 10.1016/0006-291x(89)92504-7
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575