Literature DB >> 25417102

Building robust transcriptomes with master splicing factors.

Mohini Jangi1, Phillip A Sharp2.   

Abstract

Coherent splicing networks arise from many discrete splicing decisions regulated in unison. Here, we examine the properties of robust, context-specific splicing networks. We propose that a subset of key splicing regulators, or "master splicing factors," respond to environmental cues to establish and maintain tissue transcriptomes during development.

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Year:  2014        PMID： 25417102      PMCID： PMC4243530          DOI： 10.1016/j.cell.2014.09.054

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  98 in total

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  73 in total

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