Literature DB >> 25415702

Radiation dose reduction at MDCT with iterative reconstruction for prenatal diagnosis of skeletal dysplasia: preliminary study using normal fetal specimens.

Chihiro Tani1, Yoshinori Funama, Chikako Fujioka, Yuko Nakamura, Daisuke Komoto, Hirohiko Aoyama, Kazuo Awai.   

Abstract

OBJECTIVE: The purpose of this study was to investigate to what degree the radiation dose can be reduced without affecting the ability to evaluate normal fetal bones at MDCT with iterative reconstruction.
MATERIALS AND METHODS: Fifteen normal fetal specimens immersed in containers (30- and 35-cm diameter) were scanned with a 64-MDCT scanner, with tube voltage of 100 kVp and tube current of 600, 300, 150, 100, and 50 mA. Images were subjected to adaptive statistical iterative reconstruction (ASIR). The fetal dose was measured using glass dosimeters. We calculated the relative ratio of the dose at 600 mA. Image quality was evaluated on maximum-intensity-projection and volume-rendering images. Two radiologists recorded the visualization scores of five regions. Images at 600 mA were considered to be standard.
RESULTS: With the 30-cm-diameter container, the fetal dose was 10.15 mGy (relative ratio, 100%) at a tube current of 600, 51% at 300, 25% at 150, 17% at 100, and 9% at 50 mA. With the 35-cm-diameter container the fetal dose was 10.01 mGy (relative ratio, 100%) at 600, 47% at 300, 24% at 150, 17% at 100, and 8% at 50 mA. Visual evaluation showed that in both containers, with ASIR 90%, there was a statistically significant difference between 50-and 600-mA images (p<0.01) but not between 600-mA images and those acquired at 100, 150, and 300 mA (p=0.08-1.00).
CONCLUSION: The fetal radiation dose for the evaluation of normal fetal bones can be reduced by 83% with ASIR 90%.

Entities:  

Keywords:  fetal CT; fetal radiation dose; iterative reconstruction; prenatal imaging; skeletal dysplasia

Mesh:

Year:  2014        PMID: 25415702     DOI: 10.2214/AJR.13.11578

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  2 in total

1.  T2*-weighted MRI produces viable fetal "Black-Bone" contrast with significant benefits when compared to current sequences.

Authors:  Alex Francis Goodall; Alex Barrett; Elspeth Whitby; Andrew Fry
Journal:  Br J Radiol       Date:  2021-05-21       Impact factor: 3.629

2.  Demonstration of Human Fetal Bone Morphology with MR Imaging: A Preliminary Study.

Authors:  Yoshiko Matsubara; Toru Higaki; Chihiro Tani; Shogo Kamioka; Kuniaki Harada; Hirohiko Aoyama; Yuko Nakamura; Tomoyuki Akita; Kazuo Awai
Journal:  Magn Reson Med Sci       Date:  2019-10-15       Impact factor: 2.471

  2 in total

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