| Literature DB >> 2541556 |
C P Hum1, M L Dyall-Smith, I H Holmes.
Abstract
The human rotavirus isolate B37 has a characteristic "super-short" RNA electropherotype and has been shown to represent a new VP7 serotype (M. J. Albert, L. E. Unicomb, and R. F. Bishop, 1987, J. Clin. Microbiol. 25, 183-185). The VP7 gene was cloned, and its nucleotide and predicted amino acid sequences were compared to other published VP7 gene sequences. Consistent with the serological evidence, two major antigenic regions of the B37 VP7 (i.e., regions A and B) differ in sequence from those of other G serotypes. Unexpectedly, the C antigenic region shows close similarity to G3 rotaviruses, but we were unable to detect a serological relationship using serotype 3 monoclonal antibodies.Entities:
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Year: 1989 PMID： 2541556 DOI： 10.1016/0042-6822(89)90351-6
Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616