Literature DB >> 25413661

The effect of early catch-up growth on health and well-being in young adults.

Paula van Dommelen1, Sylvia M van der Pal, Jack Bennebroek Gravenhorst, Frans J Walther, Jan M Wit, Karin M van der Pal de Bruin.   

Abstract

AIM: To study the effect of catch-up growth in the 1st year on cognition, health-related quality of life (HRQoL), problem behavior and growth in young adults.
METHODS: We included individuals without severe complications and born small for gestational age (SGA; n = 228 for weight, n = 203 for length) or with a low head circumference (HC, n = 178) or a low weight adjusted for length (n = 64) in the Collaborative Project on Preterm and SGA Infants. Neonatal growth was standardized (standard deviation scores for gestational age, SDSGA) according to GA-specific reference charts. Catch-up growth was defined as SDSGA at 1 year of age adjusted for SDSGA at birth. Cognition was defined by the Multicultural Capacity Test-Intermediate Level, HRQoL by the London Handicap Scale (LHS) and the Health Utility Index Mark 3 categorized into 4 levels (Multi-Attribute Utility, MAU), and problem behavior by the Young Adult Self-Report. We adjusted for potential confounders.
RESULTS: Most adults were born preterm (93.7%). A higher catch-up growth in the 1st year was associated with better cognition (B = 2.57, 95% CI 0.08-5.05 for weight), less disabilities according to the LHS (B = 2.06, 95% CI 0.35-3.78 for HC) and the MAU (OR = 0.67, 95% CI 0.48-0.95 for HC) and higher final height (B = 0.33, 95% CI 0.18-0.47 for weight; B = 0.41, 95% 0.28-0.55 for length, and B = 0.18, 95% CI 0.04-0.33 for HC) in young adulthood.
CONCLUSION: There are long-term benefits of catch-up growth.
© 2014 S. Karger AG, Basel.

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Mesh:

Year:  2014        PMID: 25413661     DOI: 10.1159/000364884

Source DB:  PubMed          Journal:  Ann Nutr Metab        ISSN: 0250-6807            Impact factor:   3.374


  4 in total

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  4 in total

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