| Literature DB >> 25413444 |
Alessandro Poma1, Heli Brahmbhatt, Hannah M Pendergraff, Jonathan K Watts, Nicholas W Turner.
Abstract
A strategy to exploit aptamers as recognition elements of molecularly imprinted polymeric nanoparticles (AptaMIP NPs) is presented, via modification of the chemical structure of the DNA. It is demonstrated that the introduction of this modified "aptamer monomer" results in an increase of the affinity of the produced MIP NPs, without altering their physical properties such as size, shape, or dispersibility.Entities:
Keywords: aptamers; cocaine; molecularly imprinted polymers; nanoparticles; solid-phase synthesis
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Year: 2014 PMID： 25413444 DOI： 10.1002/adma.201404235
Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849