Literature DB >> 25413421

Dosimetric impact of the AeroForm tissue expander in postmastectomy radiation therapy: an ex vivo analysis.

Janaki Moni1, Jonathan Saleeby2, Elizabeth Bannon2, Yuan-Chyuan Lo2, Thomas J Fitzgerald2.   

Abstract

PURPOSE: To evaluate the effect of the AeroForm (AirXpanders Inc, Palo Alto, CA) tissue expander on the dose distribution in a phantom from a simulated postmastectomy radiation treatment for breast cancer. METHODS AND MATERIALS: Experiments were conducted to determine the effect on the dose distribution with the metallic reservoir irradiated independently and with the entire AeroForm tissue expander placed on a RANDO phantom (The Phantom Laboratory, Salem, NY). The metallic reservoir was irradiated on a block of solid water with film at various depths ranging from 0 to 8.2 cm from the surface. The intact 400 cc AeroForm was inflated to full capacity and irradiated while positioned on a RANDO phantom, with 12 optically stimulated luminescent dosimeters (OSLDs) placed at clinically relevant expander-tissue interface points.
RESULTS: Film dosimetry with the reservoir perpendicular to film reveals 40% transmission at a depth of 0.7 cm, which increases to 60% at a depth of 8.2 cm. In the parallel position, the results vary depending on which area under the reservoir is examined, indicating that the reservoir is not a uniformly dense object. Testing of the intact expander on the phantom revealed that the average percent difference (measured vs expected dose) was 2.7%, σ = 6.2% with heterogeneity correction and 3.7%, σ = 2.4% without heterogeneity correction. The only position where the OSLD readings were consistently higher than the calculated dose by >5% was at position 1, just deep to the canister at the expander-phantom interface. At this position, the readings varied from 5.2% to 14.5%, regardless of heterogeneity correction.
CONCLUSIONS: Film dosimetry demonstrated beam attenuation in the shadow of the metallic reservoir in the expander. This decrease in dose was not reproduced on the intact expander on the phantom designed to replicate a clinical setup.
Copyright © 2015 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2014        PMID: 25413421     DOI: 10.1016/j.prro.2014.04.001

Source DB:  PubMed          Journal:  Pract Radiat Oncol        ISSN: 1879-8500


  4 in total

1.  Dosimetric analysis of the effects of a temporary tissue expander on the radiotherapy technique.

Authors:  So Hyun Park; Young Suk Kim; Jinhyun Choi
Journal:  Radiol Med       Date:  2020-10-06       Impact factor: 3.469

2.  Prepectoral 2-stage Breast Reconstruction with Carbon Dioxide Tissue Expansion.

Authors:  Franca S Kraenzlin; Halley Darrach; Karan Chopra; Gedge D Rosson; Kristen P Broderick; Justin M Sacks
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-05-27

3.  A dosimetry study of post-mastectomy radiation therapy with AeroForm tissue expander.

Authors:  Seng Boh Lim; Li Cheng Kuo; Guang Li; Hsiang-Chi Kuo; Beryl McCormick; Oren Cahlon; Simon Powell; Linda X Hong
Journal:  J Appl Clin Med Phys       Date:  2020-07-02       Impact factor: 2.102

4.  Two-stage Prosthetic Prepectoral Breast Reconstruction: Comparing Tissue Expansion with Carbon Dioxide and Saline.

Authors:  Karan Chopra; Devinder Singh; Nick Hricz; Kylie Brassard; Virginia Orlov; Luther H Holton Iii
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-03-25
  4 in total

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