Literature DB >> 25412860

Micro RNA: an epigenetic regulator of type 2 diabetes.

Vinitha Kadamkode, Gautam Banerjee1.   

Abstract

Type 2 Diabetes is a complex disease with multifactorial pathogenesis. The interplay between genes and lifestyle changes complicates the etiology of the disease. In spite of growing number of attempts to unravel the mechanism of this metabolic disease, the molecular nature of type 2 Diabetes is not fully understood. The discovery of a new class of non-coding RNAs, micro RNAs and their role in regulation of gene expression have paved the way for better understanding of disease pathogenesis. Increasing number of evidences suggest crucial role of miRNAs in insulin resistance and β cell dysfunction, which are the two main features of type 2 Diabetes. This review summarizes the role of miRNA in elicitation and progression of type 2 Diabetes.

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Year:  2014        PMID： 25412860     DOI： 10.2174/2211536603666141118232514

Source DB:  PubMed          Journal:  Microrna


  10 in total

Review 1.  Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders.

Authors:  Virginie Gillet; Darel John Hunting; Larissa Takser
Journal:  Curr Environ Health Rep       Date:  2016-09

2.  hsa-miR-4485 regulates mitochondrial functions and inhibits the tumorigenicity of breast cancer cells.

Authors:  Lakshmi Sripada; Kritarth Singh; Anastasiya V Lipatova; Aru Singh; Paresh Prajapati; Dhanendra Tomar; Khyati Bhatelia; Milton Roy; Rochika Singh; Madan M Godbole; Peter M Chumakov; Rajesh Singh
Journal:  J Mol Med (Berl)       Date:  2017-02-20       Impact factor: 4.599

3.  A decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice.

Authors:  Caifeng Yan; Jinfeng Chen; Min Li; Wenying Xuan; Dongming Su; Hui You; Yujie Huang; Nuoqi Chen; Xiubin Liang
Journal:  Diabetologia       Date:  2016-03-22       Impact factor: 10.122

4.  miR-344-5p Modulates Cholesterol-Induced β-Cell Apoptosis and Dysfunction Through Regulating Caveolin-1 Expression.

Authors:  Xulong Sun; Guangnian Ji; Pengzhou Li; Weizheng Li; Jun Li; Liyong Zhu
Journal:  Front Endocrinol (Lausanne)       Date:  2021-07-28       Impact factor: 5.555

5.  Epigenetic mechanisms of endothelial dysfunction in type 2 diabetes.

Authors:  Francesco Prattichizzo; Angelica Giuliani; Artan Ceka; Maria Rita Rippo; Anna Rita Bonfigli; Roberto Testa; Antonio Domenico Procopio; Fabiola Olivieri
Journal:  Clin Epigenetics       Date:  2015-05-23       Impact factor: 6.551

6.  Urinary chromium is associated with changes in leukocyte miRNA expression in obese subjects.

Authors:  L Dioni; S Sucato; V Motta; S Iodice; L Angelici; C Favero; T Cavalleri; L Vigna; B Albetti; S Fustinoni; P Bertazzi; A Pesatori; V Bollati
Journal:  Eur J Clin Nutr       Date:  2016-10-12       Impact factor: 4.016

7.  Improved systemic metabolism and adipocyte biology in miR-150 knockout mice.

Authors:  Minsung Kang; Xiaobing Liu; Yuchang Fu; W Timothy Garvey
Journal:  Metabolism       Date:  2018-01-31       Impact factor: 8.694

Review 8.  Complex interactomes and post-translational modifications of the regulatory proteins HABP4 and SERBP1 suggest pleiotropic cellular functions.

Authors:  Carolina Colleti; Talita Diniz Melo-Hanchuk; Flávia Regina Moraes da Silva; Ângela Saito; Jörg Kobarg
Journal:  World J Biol Chem       Date:  2019-11-21

Review 9.  Significant Association between Microrna Gene Polymorphisms and Type 2 Diabetes Mellitus Susceptibility in Asian Population: A Meta-Analysis.

Authors:  Zhifang Deng; Wenqi Gao; Wei Luo; Li Ai; Min Hu
Journal:  Iran J Public Health       Date:  2020-05       Impact factor: 1.429

Review 10.  circRNAs Signature as Potential Diagnostic and Prognostic Biomarker for Diabetes Mellitus and Related Cardiovascular Complications.

Authors:  Mohamed Zaiou
Journal:  Cells       Date:  2020-03-09       Impact factor: 6.600
  10 in total

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