Literature DB >> 2541066

Mapping and characterization of an X-linked processed gene related to MYCL1.

C C Morton1, M C Nussenzweig, R Sousa, G D Sorenson, O S Pettengill, T B Shows.   

Abstract

A DNA sequence with homology to the myc family of proto-oncogenes has been characterized and found to be a processed gene related to L-MYC (MYCL1). This processed gene (MYCL2) was isolated by cross-hybridization to an oligonucleotide probe synthesized from the C-MYC (MYC) sequence in a highly conserved region of the myc gene family. Sequence analysis of MYCL2 revealed an open reading frame of 1194 bp with no intervening sequences and strong homology to the recently published DNA sequence of MYCL1. Southern and Northern blot analyses of DNAs and RNAs from small cell lung carcinomas confirmed its MYCL1 homology. Mapping of MYCL2 by somatic cell hybrids places this sequence on the long arm of the X chromosome in bands q22----q28.

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Year:  1989        PMID: 2541066     DOI: 10.1016/0888-7543(89)90344-3

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  8 in total

1.  Testis-specific expression of the human MYCL2 gene.

Authors:  N G Robertson; R J Pomponio; G L Mutter; C C Morton
Journal:  Nucleic Acids Res       Date:  1991-06-11       Impact factor: 16.971

Review 2.  An overview of MYC and its interactome.

Authors:  Maralice Conacci-Sorrell; Lisa McFerrin; Robert N Eisenman
Journal:  Cold Spring Harb Perspect Med       Date:  2014-01-01       Impact factor: 6.915

Review 3.  Reverse transcriptase: mediator of genomic plasticity.

Authors:  J Brosius; H Tiedge
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

4.  Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner.

Authors:  W R Atchley; W M Fitch
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

5.  Genetic alterations associated with progression from pancreatic intraepithelial neoplasia to invasive pancreatic tumor.

Authors:  Stephen J Murphy; Steven N Hart; Joema Felipe Lima; Benjamin R Kipp; Mitchell Klebig; Jennifer L Winters; Csilla Szabo; Lizhi Zhang; Bruce W Eckloff; Gloria M Petersen; Steven E Scherer; Richard A Gibbs; Robert R McWilliams; George Vasmatzis; Fergus J Couch
Journal:  Gastroenterology       Date:  2013-08-02       Impact factor: 22.682

6.  Evolution of the Max and Mlx networks in animals.

Authors:  Lisa G McFerrin; William R Atchley
Journal:  Genome Biol Evol       Date:  2011-08-22       Impact factor: 3.416

7.  Origins of Myc proteins--using intrinsic protein disorder to trace distant relatives.

Authors:  Amir Mahani; Johan Henriksson; Anthony P H Wright
Journal:  PLoS One       Date:  2013-09-24       Impact factor: 3.240

8.  A male infant with Xq22.2q22.3 duplication containing PLP1 and MID2.

Authors:  Swati R Chanchani; Hongyan Xie; Gurbax Sekhon; Ana M Melikishvili; Sue Moyer Harasink; Harpreet Pall; Philip F Giampietro
Journal:  Mol Genet Genomic Med       Date:  2020-01-17       Impact factor: 2.183

  8 in total

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