Literature DB >> 25409938

Role of operative airway evaluation in children with recurrent croup: a retrospective cohort study.

M Duval1, G Tarasidis1, J F Grimmer1, H R Muntz1, A H Park1, M Smith1, F Asfour2, J Meier1.   

Abstract

OBJECTIVE: Determine which risk factors in children with recurrent croup warrant bronchoscopic evaluation.
DESIGN: Retrospective cohort study.
SETTING: Tertiary paediatric hospital. PARTICIPANTS: Children with recurrent croup who underwent a rigid bronchoscopy between 2001 and 2013. MAIN OUTCOME MEASURES: Bronchoscopy findings, classified as normal, mildly abnormal or significantly abnormal.
RESULTS: Two hundred and thirty-five children underwent a rigid bronchoscopy and 110 underwent a flexible oesophagoscopy. One hundred and forty-five children (61.7%) had a mildly abnormal exam, and 27 children (11.5%) had significant findings that required a surgical intervention or grade 2 or greater subglottic stenosis. The significantly abnormal group included 4 children with laryngomalacia, 2 with a subglottic cyst, 8 with grade 2 or 3 subglottic stenosis and 13 children who underwent a surgical procedure for subglottic stenosis. Sixty-seven children had a preoperative diagnosis of asthma, 62 were atopic and 78 had symptoms of gastro-oesophageal reflux. Oesophagoscopy was diagnostic of gastro-oesophageal reflux in 19 of 110 cases, and 106 children (45.1%) had bronchoscopic findings suggestive of GERD. Eight children had eosinophilic oesophagitis. After multivariate analysis, significantly abnormal bronchoscopy was significantly associated with chronic cough (P = 0.02), have a previous intubation (P = 0.002) or be younger than 3 years old (P = 0.01).
CONCLUSION: Significant findings on bronchoscopy that warranted further surgical intervention were uncommon in this cohort. Nearly half of the patients had evidence of gastro-oesophageal reflux. In patients without risk factors for significant abnormalities, empiric medical management may be beneficial prior to endoscopy.
© 2014 John Wiley & Sons Ltd.

Entities:  

Mesh:

Year:  2015        PMID: 25409938     DOI: 10.1111/coa.12353

Source DB:  PubMed          Journal:  Clin Otolaryngol        ISSN: 1749-4478            Impact factor:   2.597


  1 in total

Review 1.  A multi-disciplinary approach to chronic cough in children.

Authors:  Shraddha S Mukerji; Naga Jaya Smitha Yenduri; Eric Chiou; Siby P Moonnumakal; Joshua R Bedwell
Journal:  Laryngoscope Investig Otolaryngol       Date:  2022-03-23
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.