Literature DB >> 25409602

Lipid nanoparticles for gene delivery.

Yi Zhao1, Leaf Huang1.   

Abstract

Nonviral vectors which offer a safer and versatile alternative to viral vectors have been developed to overcome problems caused by viral carriers. However, their transfection efficacy or level of expression is substantially lower than viral vectors. Among various nonviral gene vectors, lipid nanoparticles are an ideal platform for the incorporation of safety and efficacy into a single delivery system. In this chapter, we highlight current lipidic vectors that have been developed for gene therapy of tumors and other diseases. The pharmacokinetic, toxic behaviors and clinic trials of some successful lipids particles are also presented.

Entities:  

Keywords:  Gene delivery; Lipid nanoparticles

Mesh：

Substances：

Year:  2014        PMID： 25409602      PMCID： PMC5006671          DOI： 10.1016/B978-0-12-800148-6.00002-X

Source DB:  PubMed          Journal:  Adv Genet        ISSN： 0065-2660            Impact factor:   1.944


  91 in total

1.  Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus.

Authors:  S Brunner; T Sauer; S Carotta; M Cotten; M Saltik; E Wagner
Journal:  Gene Ther       Date:  2000-03       Impact factor: 5.250

2.  Influence of polyethylene glycol density and surface lipid on pharmacokinetics and biodistribution of lipid-calcium-phosphate nanoparticles.

Authors:  Yang Liu; Yunxia Hu; Leaf Huang
Journal:  Biomaterials       Date:  2014-01-02       Impact factor: 12.479

3.  Metabolism studies of unformulated internally [3H]-labeled short interfering RNAs in mice.

Authors:  Jesper Christensen; Karine Litherland; Thomas Faller; Esther van de Kerkhof; François Natt; Jürg Hunziker; Joel Krauser; Piet Swart
Journal:  Drug Metab Dispos       Date:  2013-03-22       Impact factor: 3.922

4.  Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes.

Authors:  E T Dams; P Laverman; W J Oyen; G Storm; G L Scherphof; J W van Der Meer; F H Corstens; O C Boerman
Journal:  J Pharmacol Exp Ther       Date:  2000-03       Impact factor: 4.030

5.  Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

Authors:  Yizhou Dong; Kevin T Love; J Robert Dorkin; Sasilada Sirirungruang; Yunlong Zhang; Delai Chen; Roman L Bogorad; Hao Yin; Yi Chen; Arturo J Vegas; Christopher A Alabi; Gaurav Sahay; Karsten T Olejnik; Weiheng Wang; Avi Schroeder; Abigail K R Lytton-Jean; Daniel J Siegwart; Akin Akinc; Carmen Barnes; Scott A Barros; Mary Carioto; Kevin Fitzgerald; Julia Hettinger; Varun Kumar; Tatiana I Novobrantseva; June Qin; William Querbes; Victor Koteliansky; Robert Langer; Daniel G Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-10       Impact factor: 11.205

6.  Microarray analysis of the toxicogenomics and the genotoxic potential of a cationic lipid-based gene delivery nanosystem in human alveolar epithelial a549 cells.

Authors:  Yadollah Omidi; Jaleh Barar; Hamid Reza Heidari; Somaieh Ahmadian; Hossein Ahmadpour Yazdi; Saghir Akhtar
Journal:  Toxicol Mech Methods       Date:  2008       Impact factor: 2.987

7.  Explorations of high-intensity therapeutic ultrasound and microbubble-mediated gene delivery in mouse liver.

Authors:  S Song; Z Shen; L Chen; A A Brayman; C H Miao
Journal:  Gene Ther       Date:  2011-03-31       Impact factor: 5.250

Review 8.  Gene therapy of liver diseases: a 2011 perspective.

Authors:  Gloria Gonzalez-Aseguinolaza; Jesús Prieto
Journal:  Clin Res Hepatol Gastroenterol       Date:  2011-07-22       Impact factor: 2.947

9.  A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo.

Authors:  Yusuke Sato; Hiroto Hatakeyama; Yu Sakurai; Mamoru Hyodo; Hidetaka Akita; Hideyoshi Harashima
Journal:  J Control Release       Date:  2012-09-20       Impact factor: 9.776

10.  Biodistribution and gene expression of lipid/plasmid complexes after systemic administration.

Authors:  R I Mahato; K Anwer; F Tagliaferri; C Meaney; P Leonard; M S Wadhwa; M Logan; M French; A Rolland
Journal:  Hum Gene Ther       Date:  1998-09-20       Impact factor: 5.695
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  20 in total

1.  Co-delivery of mRNA and SPIONs through amino-ester nanomaterials.

Authors:  Xiao Luo; Weiyu Zhao; Bin Li; Xinfu Zhang; Chengxiang Zhang; Anna Bratasz; Binbin Deng; David W McComb; Yizhou Dong
Journal:  Nano Res       Date:  2018-05-12       Impact factor: 8.897

Review 2.  Gene Therapy: Will the Promise of Optimizing Lung Allografts Become Reality?

Authors:  Qimeng Gao; Isabel F DeLaura; Imran J Anwar; Samuel J Kesseli; Riley Kahan; Nader Abraham; Aravind Asokan; Andrew S Barbas; Matthew G Hartwig
Journal:  Front Immunol       Date:  2022-07-01       Impact factor: 8.786

Review 3.  Cancer-Targeting Nanoparticles for Combinatorial Nucleic Acid Delivery.

Authors:  Hannah J Vaughan; Jordan J Green; Stephany Y Tzeng
Journal:  Adv Mater       Date:  2019-06-20       Impact factor: 30.849

Review 4.  Delivery technologies for in utero gene therapy.

Authors:  Rohan Palanki; William H Peranteau; Michael J Mitchell
Journal:  Adv Drug Deliv Rev       Date:  2020-11-09       Impact factor: 15.470

Review 5.  Cancer immunotherapies revisited: state of the art of conventional treatments and next-generation nanomedicines.

Authors:  Coral García-Fernández; Anna Saz; Cristina Fornaguera; Salvador Borrós
Journal:  Cancer Gene Ther       Date:  2021-04-09       Impact factor: 5.987

Review 6.  A review of the tortuous path of nonviral gene delivery and recent progress.

Authors:  Divya Sharma; Sanjay Arora; Jagdish Singh; Buddhadev Layek
Journal:  Int J Biol Macromol       Date:  2021-06-01       Impact factor: 8.025

7.  Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

Authors:  Jung-Chien Cheng; Hsun-Ming Chang; Siyuan Xiong; Wai-Kin So; Peter C K Leung
Journal:  Oncotarget       Date:  2016-12-06

8.  Preparing for Pandemics: RNA Vaccines at the Forefront.

Authors:  Jesse H Erasmus; Deborah Heydenburg Fuller
Journal:  Mol Ther       Date:  2020-06-23       Impact factor: 11.454

9.  Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo.

Authors:  Gabriela Arias-Alpizar; Li Kong; Redmar C Vlieg; Alexander Rabe; Panagiota Papadopoulou; Michael S Meijer; Sylvestre Bonnet; Stefan Vogel; John van Noort; Alexander Kros; Frederick Campbell
Journal:  Nat Commun       Date:  2020-07-20       Impact factor: 14.919

10.  Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome.

Authors:  Md Nazir Hossen; Lin Wang; Harisha R Chinthalapally; Joe D Robertson; Kar-Ming Fung; Stefan Wilhelm; Magdalena Bieniasz; Resham Bhattacharya; Priyabrata Mukherjee
Journal:  Sci Adv       Date:  2020-07-22       Impact factor: 14.957
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