Literature DB >> 25407241

Ascorbic acid: new role of an age-old micronutrient in the management of periodontal disease in older adults.

Adel S Alagl1, Subraya Giliyar Bhat.   

Abstract

To review the new role of an age-old micronutrient - ascorbic acid - in the management of periodontal disease. Articles pertaining to the topic were searched in PubMed and other search engines from year 1974 to April 2014 with the following key words: "ascorbic acid," "ascorbate," "vitamin C," "periodontal disease," "gingivitis," "periodontitis," "anti-oxidants" and "elderly." Balanced nutrition is an essential factor in the elderly. Modification of nutritional requirement is important to overcome the effect of an unbalanced diet in older individuals as a result of several external and internal host-associated factors. Micronutrient requirements as aging advances could change, and require due attention. Ascorbic acid and its relationship with periodontal disease are very well known. However, recent changes in the concept of understanding the pathogenicity has led to a new path of therapeutic intervention with ascorbic acid in many chronic diseases. Oxidative stress with its associated burden might alter the disease process. In the era of "periodontal medicine," the impact of remote tissue changes on systemic disease has to be taken into serious consideration. Deficiency of nutritional impact on the host, with micronutrient vitamin C detailed in this review with sources, absorption, interaction and its relationship with systemic disease, and thereby the impact on periodontal disease. Ascorbic acid plays an important role in the aging process, and in the maintenance of periodontal health in the elderly.
© 2014 Japan Geriatrics Society.

Entities:  

Keywords:  anti-oxidants; ascorbic acid; elderly; nutrition; periodontal disease; vitamin C

Mesh:

Substances:

Year:  2014        PMID: 25407241     DOI: 10.1111/ggi.12408

Source DB:  PubMed          Journal:  Geriatr Gerontol Int        ISSN: 1447-0594            Impact factor:   2.730


  13 in total

1.  Ascorbic Acid, Inflammatory Cytokines (IL-1β/TNF-α/IFN-γ), or Their Combination's Effect on Stemness, Proliferation, and Differentiation of Gingival Mesenchymal Stem/Progenitor Cells.

Authors:  Karim M Fawzy El-Sayed; Nhung Nguyen; Christof E Dörfer
Journal:  Stem Cells Int       Date:  2020-08-17       Impact factor: 5.443

Review 2.  Spontaneous preterm birth: advances toward the discovery of genetic predisposition.

Authors:  Jerome F Strauss; Roberto Romero; Nardhy Gomez-Lopez; Hannah Haymond-Thornburg; Bhavi P Modi; Maria E Teves; Laurel N Pearson; Timothy P York; Harvey A Schenkein
Journal:  Am J Obstet Gynecol       Date:  2017-12-14       Impact factor: 8.661

3.  Evaluation of the Anti-Inflammatory Effect of Locally Delivered Vitamin C in the Treatment of Persistent Gingival Inflammation: Clinical and Histopathological Study.

Authors:  Nermin M Yussif; Manar A Abdul Aziz; Ahmed R Abdel Rahman
Journal:  J Nutr Metab       Date:  2016-12-05

Review 4.  Oxidative Stress and Antioxidant System in Periodontitis.

Authors:  Yue Wang; Oleh Andrukhov; Xiaohui Rausch-Fan
Journal:  Front Physiol       Date:  2017-11-13       Impact factor: 4.566

Review 5.  Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance.

Authors:  Alfonso Varela-López; María D Navarro-Hortal; Francesca Giampieri; Pedro Bullón; Maurizio Battino; José L Quiles
Journal:  Molecules       Date:  2018-05-20       Impact factor: 4.411

6.  Effect of Vitamin C as an Adjunct in Nonsurgical Periodontal Therapy in Uncontrolled Type 2 Diabetes Mellitus Patients.

Authors:  Piyapat Kunsongkeit; Nis Okuma; Supanee Rassameemasmaung; Pechngam Chaivanit
Journal:  Eur J Dent       Date:  2019-07-07

7.  Effects of vitamin C local application on ligature-induced periodontitis in diabetic rats.

Authors:  Ayşe Toraman; Taner Arabaci; Zeliha Aytekin; Mevlüt Albayrak; Yasin Bayir
Journal:  J Appl Oral Sci       Date:  2020-11-27       Impact factor: 2.698

Review 8.  Hydrogen Sulfide, Oxidative Stress and Periodontal Diseases: A Concise Review.

Authors:  Maria Greabu; Alexandra Totan; Daniela Miricescu; Radu Radulescu; Justina Virlan; Bogdan Calenic
Journal:  Antioxidants (Basel)       Date:  2016-01-14

Review 9.  Oxidative Stress in the Local and Systemic Events of Apical Periodontitis.

Authors:  Patricia Hernández-Ríos; Pirkko J Pussinen; Rolando Vernal; Marcela Hernández
Journal:  Front Physiol       Date:  2017-11-01       Impact factor: 4.566

10.  Possible Involvement of Vitamin C in Periodontal Disease-Diabetes Mellitus Association.

Authors:  Maria Bogdan; Andreea Daniela Meca; Mihail Virgil Boldeanu; Dorin Nicolae Gheorghe; Adina Turcu-Stiolica; Mihaela-Simona Subtirelu; Lidia Boldeanu; Mihaela Blaj; Gina Eosefina Botnariu; Cristiana Elena Vlad; Liliana Georgeta Foia; Petra Surlin
Journal:  Nutrients       Date:  2020-02-20       Impact factor: 5.717

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