| Literature DB >> 25403536 |
Abstract
Here we introduce entropy-based measures derived from information theory for detecting and characterizing epistasis in genetic association studies. We provide a general overview of the methods and highlight some of the modifications that have greatly improved its power for genetic analysis. We end with a few published studies of complex human diseases that have used these measures.Entities:
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Year: 2015 PMID: 25403536 DOI: 10.1007/978-1-4939-2155-3_13
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745