John O Mason1, Shyam A Patel. 1. *Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, Alabama; and †Retina Consultants of Alabama, Callahan Eye Foundation Hospital, Birmingham, Alabama.
Abstract
PURPOSE: To report a very rare case of bilateral Bull's eye maculopathy caused by sertraline. METHODS: Clinical case report and literature review. PATIENT: A 14-year-old girl. RESULTS: A 14-year-old girl with no significant medical history developed bilateral Bull's eye maculopathy after taking sertraline for 1 year. Diagnostic work-up, which consisted of electrooculography, electroretinography, and genetic testing, yielded no abnormal results. Three-year follow-up examination after discontinuation of sertraline showed no improvement in visual acuity (20/200 bilaterally) or retinal pigment epithelium. This is the second published case, and according to the National Registry of Drug-Induced Ocular Side Effects, this is only the fifth reported case of presumed sertraline maculopathy. CONCLUSION: Although Bull's eye maculopathy related to sertraline is rare, physicians and patients need to be aware of the possible toxicity.
PURPOSE: To report a very rare case of bilateral Bull's eye maculopathy caused by sertraline. METHODS: Clinical case report and literature review. PATIENT: A 14-year-old girl. RESULTS: A 14-year-old girl with no significant medical history developed bilateral Bull's eye maculopathy after taking sertraline for 1 year. Diagnostic work-up, which consisted of electrooculography, electroretinography, and genetic testing, yielded no abnormal results. Three-year follow-up examination after discontinuation of sertraline showed no improvement in visual acuity (20/200 bilaterally) or retinal pigment epithelium. This is the second published case, and according to the National Registry of Drug-Induced Ocular Side Effects, this is only the fifth reported case of presumed sertralinemaculopathy. CONCLUSION: Although Bull's eye maculopathy related to sertraline is rare, physicians and patients need to be aware of the possible toxicity.