Literature DB >> 25401827

All-silicon monolithic Mach-Zehnder interferometer as a refractive index and bio-chemical sensor.

K Misiakos, I Raptis, E Makarona, A Botsialas, A Salapatas, P Oikonomou, A Psarouli, P S Petrou, S E Kakabakos, Kari Tukkiniemi, M Sopanen, G Jobst.   

Abstract

A complete Mach-Zehnder interferometer monolithically integrated on silicon is presented and employed as a refractive index and bio-chemical sensor. The device consists of broad-band light sources optically coupled to photodetectors through monomodal waveguides forming arrays of Mach-Zehnder interferometers, all components being monolithically integrated on silicon through mainstream silicon technology. The interferometer is photonically engineered in a way that the phase difference of light travelling through the sensing and reference arms is approximately wavelength independent. Consequently, upon effective medium changes, it becomes feasible even with a broad-band source to induce sinusoidal-type of detector photocurrents similar to the classical monochromatic counterparts. The device is completed with its fluidic and interconnect components so that on chip interferometric measurements can be performed. Examples of refractive index and protein sensing are presented to establish the potential of the proposed device for real-time in situ monitoring applications. This is the only silicon device that has achieved complete on-chip interferometry.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 25401827     DOI: 10.1364/OE.22.026803

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  5 in total

Review 1.  Last Advances in Silicon-Based Optical Biosensors.

Authors:  Adrián Fernández Gavela; Daniel Grajales García; Jhonattan C Ramirez; Laura M Lechuga
Journal:  Sensors (Basel)       Date:  2016-02-24       Impact factor: 3.576

2.  Mycotoxin Biosensor Based on Optical Planar Waveguide.

Authors:  Ali Al-Jawdah; Alexei Nabok; Radhyah Jarrah; Alan Holloway; Anna Tsargorodska; Eszter Takacs; Andras Szekacs
Journal:  Toxins (Basel)       Date:  2018-07-03       Impact factor: 4.546

3.  Study on the limit of detection in MZI-based biosensor systems.

Authors:  Daan Martens; Peter Bienstman
Journal:  Sci Rep       Date:  2019-04-08       Impact factor: 4.379

4.  Highly sensitive label-free in vitro detection of aflatoxin B1 in an aptamer assay using optical planar waveguide operating as a polarization interferometer.

Authors:  Ali Al-Jawdah; Alexei Nabok; Hisham Abu-Ali; Gaelle Catanante; Jean-Louis Marty; Andras Szekacs
Journal:  Anal Bioanal Chem       Date:  2019-08-07       Impact factor: 4.142

5.  Monolithically integrated broad-band Mach-Zehnder interferometers for highly sensitive label-free detection of biomolecules through dual polarization optics.

Authors:  A Psarouli; A Salapatas; A Botsialas; P S Petrou; I Raptis; E Makarona; G Jobst; K Tukkiniemi; M Sopanen; R Stoffer; S E Kakabakos; K Misiakos
Journal:  Sci Rep       Date:  2015-12-02       Impact factor: 4.379

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.