Literature DB >> 25401684

Iron- and cobalt-catalyzed arylation of azetidines, pyrrolidines, and piperidines with Grignard reagents.

Baptiste Barré1, Laurine Gonnard1, Rémy Campagne1, Sébastien Reymond1, Julien Marin2, Paola Ciapetti2, Marie Brellier2, Amandine Guérinot1, Janine Cossy1.   

Abstract

Iron- and cobalt-catalyzed cross-couplings between iodo-azetidines, -pyrrolidines, -piperidines, and Grignard reagents are disclosed. The reaction is efficient, cheap, chemoselective and tolerates a large variety of (hetero)aryl Grignard reagents.

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Year:  2014        PMID： 25401684     DOI： 10.1021/ol503043r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Organic chemistry. Strain-release amination.

Authors:  Ryan Gianatassio; Justin M Lopchuk; Jie Wang; Chung-Mao Pan; Lara R Malins; Liher Prieto; Thomas A Brandt; Michael R Collins; Gary M Gallego; Neal W Sach; Jillian E Spangler; Huichin Zhu; Jinjiang Zhu; Phil S Baran
Journal:  Science       Date:  2016-01-15       Impact factor: 47.728

Review 2.  Cobalt-Catalyzed (Hetero)arylation of Saturated Cyclic Amines with Grignard Reagents.

Authors:  Baptiste Barré; Laurine Gonnard; Amandine Guérinot; Janine Cossy
Journal:  Molecules       Date:  2018-06-14       Impact factor: 4.411
  2 in total

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