[Antioxidant activity of ubiquinone-9 and its combinations with vitamin E and sodium selenite in toxic lesions of the liver].

It was established that ubiquinone-9 (30 mg/kg per course) decreases in rats the content of primary products of lipid peroxidation--diene conjugates--in the liver by 12 times greater than vitamin E (a course dose of 30 mg/kg). Ubiquinone-9, vitamin E and sodium selenite (a course dose of 90 mg/kg) equally reduced the content of a secondary product of lipid peroxidation--malon dialdehyde. In this case the activity of sodium selenite was 300 times higher than the activity of ubiquinone-9 and vitamin E. The use of ubiquinone-9 in combination with vitamin E and sodium selenite potentiated the antioxidant effect.