| Literature DB >> 25400013 |
Reza Sadjadi1, Mary M Reilly, Michael E Shy, Davide Pareyson, Matilde Laura, Sinead Murphy, Shawna M E Feely, Tiffany Grider, Chelsea Bacon, Giuseppe Piscosquito, Daniela Calabrese, Ted M Burns.
Abstract
Charcot-Marie-Tooth Neuropathy Score second version (CMTNSv2) is a validated clinical outcome measure developed for use in clinical trials to monitor disease impairment and progression in affected CMT patients. Currently, all items of CMTNSv2 have identical contribution to the total score. We used Rasch analysis to further explore psychometric properties of CMTNSv2, and in particular, category response functioning, and their weight on the overall disease progression. Weighted category responses represent a more accurate estimate of actual values measuring disease severity and therefore could potentially be used in improving the current version.Entities:
Keywords: Charcot-Marie-Tooth; Charcot-Marie-Tooth Neuropathy Score (CMTNS2) second version; Rasch analysis; outcome measures; psychometrics
Mesh:
Year: 2014 PMID: 25400013 PMCID: PMC4303498 DOI: 10.1111/jns.12084
Source DB: PubMed Journal: J Peripher Nerv Syst ISSN: 1085-9489 Impact factor: 3.494