Marco Scala1, Silvia Lenarduzzi2, Francesco Spagnolo1, Maria Trapasso3, Chiara Ottonello4, Anita Muraglia4, Annalisa Barla5, Margherita Squillario, Paolo Strada. 1. Department of Plastic and Reconstructive Surgery, IRCCS Azienda Ospedaliera Universitaria San Martino, Istituto Nazionale Per La Ricerca Sul Cancro, Genova, Italy. 2. Department of Medical and Veterinary Sciences, University of Parma, Parma, Italy. 3. Department of Plastic and Reconstructive Surgery, IRCCS Azienda Ospedaliera Universitaria San Martino, Istituto Nazionale Per La Ricerca Sul Cancro, Genova, Italy trapassomaria1984@gmail.com. 4. Department of Experimental Medicine, University of Genova, Genova, Italy. 5. Department of Computer and Information Science (DISI), University of Genova, Genova, Italy.
Abstract
BACKGROUND/AIM: The aim of the present study was to evaluate the safety and the clinical outcome of platelet-rich plasma for the treatment of teno-desmic injures in competition horses. PATIENTS AND METHODS: From January 2009 to December 2011, 150 sport horses suffering from teno-desmic injuries were treated with no-gelled platelet-concentrate. RESULTS: No horse showed any major adverse reaction as a result of the procedure. Full healing was obtained for 81% of the horses. Twelve percent had clinical improvement and only 7% a failure. Eight percent of cases of relapse were observed. No statistically significant correlation existed between clinical outcome and the area of the lesion. A statistically significant correlation existed between the clinical outcome and the age of the horse. CONCLUSION: Treatment with platelet-derived growth factors leads to the formation of a tendon with normal morphology and functionality, which translate in the resumption of the agonistic activity for the horses we treated.
BACKGROUND/AIM: The aim of the present study was to evaluate the safety and the clinical outcome of platelet-rich plasma for the treatment of teno-desmic injures in competition horses. PATIENTS AND METHODS: From January 2009 to December 2011, 150 sport horses suffering from teno-desmic injuries were treated with no-gelled platelet-concentrate. RESULTS: No horse showed any major adverse reaction as a result of the procedure. Full healing was obtained for 81% of the horses. Twelve percent had clinical improvement and only 7% a failure. Eight percent of cases of relapse were observed. No statistically significant correlation existed between clinical outcome and the area of the lesion. A statistically significant correlation existed between the clinical outcome and the age of the horse. CONCLUSION: Treatment with platelet-derived growth factors leads to the formation of a tendon with normal morphology and functionality, which translate in the resumption of the agonistic activity for the horses we treated.
Authors: Marco Viganò; Irene Tessaro; Letizia Trovato; Alessandra Colombini; Marco Scala; Alberto Magi; Andrea Toto; Giuseppe Peretti; Laura de Girolamo Journal: J Orthop Surg Res Date: 2018-11-06 Impact factor: 2.359