Literature DB >> 25398562

Abrupt nicotine reduction as an endgame policy: a randomised trial.

Natalie Walker1, Trish Fraser2, Colin Howe1, Murray Laugesen3, Penny Truman4, Varsha Parag1, Marewa Glover5, Chris Bullen1.   

Abstract

OBJECTIVE: To determine if smokers unmotivated to quit reduce usual cigarette consumption when cigarettes priced according to nicotine content are made available.
METHODS: Randomised, parallel-group, trial (ACTRN12612000914864) undertaken in Wakatipu/Central Otago, New Zealand. Dependent adult daily smokers unmotivated to quit were randomly allocated to an intervention group provided with 12 weeks supply of free very low nicotine content (VLNC) cigarettes, or to a control group, who were free to purchase their usual cigarette brand over the same period. The primary outcome was change from baseline in the daily mean number of usual cigarettes smoked over the previous week, measured at 12 weeks. Secondary outcomes at 6 and 12 weeks included cigarettes smoked per week (also measured at weeks 1-6 and 9), salivary cotinine, tobacco dependence, smoking satisfaction/craving, behavioural addiction to smoking, autonomy over smoking, motivation to stop, price at which participants would purchase VLNC cigarettes, quitting and adverse events.
RESULTS: Thirty-three smokers were randomised (17 intervention, 16 control). A NZ$15 price differential (per pack of 20) based on nicotine content led to a halving in the mean number of cigarettes smoked per day over the previous week, a reduction in tobacco dependence and an increase in quitting. Intervention participants smoked a similar total number of cigarettes (usual plus VLNC) as those in the control group, exposing them to a similar level of toxicants.
CONCLUSIONS: Smokers unmotivated to quit reduce their usual cigarette consumption (and thus nicotine exposure) when VLNC cigarettes are made available at a significantly reduced price. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Entities:  

Keywords:  End game; Nicotine; Price; Public policy; Taxation

Mesh:

Year:  2014        PMID: 25398562     DOI: 10.1136/tobaccocontrol-2014-051801

Source DB:  PubMed          Journal:  Tob Control        ISSN: 0964-4563            Impact factor:   7.552


  12 in total

1.  Public misperception that very low nicotine cigarettes are less carcinogenic.

Authors:  M Justin Byron; Michelle Jeong; David B Abrams; Noel T Brewer
Journal:  Tob Control       Date:  2018-01-23       Impact factor: 7.552

2.  Exposure to smoke from high- but not low-nicotine cigarettes leads to signs of dependence in male rats and potentiates the effects of nicotine in female rats.

Authors:  Ranjithkumar Chellian; Azin Behnood-Rod; Ryann Wilson; Isaac Wilks; Parker Knight; Marcelo Febo; Adriaan W Bruijnzeel
Journal:  Pharmacol Biochem Behav       Date:  2020-07-16       Impact factor: 3.533

3.  Perceptions of Nicotine Reduction Policy in the United States: A Qualitative Study.

Authors:  Katherine C Henderson; Emily E Loud; Hue Trong Duong; Reed M Reynolds; Bo Yang; Charity A Ntansah; David L Ashley; James F Thrasher; Lucy Popova
Journal:  Nicotine Tob Res       Date:  2022-08-06       Impact factor: 5.825

4.  Behavioral Economic Purchase Tasks to Estimate Demand for Novel Nicotine/tobacco Products and Prospectively Predict Future Use: Evidence From The Netherlands.

Authors:  Bryan W Heckman; K Michael Cummings; Georges J Nahas; Marc C Willemsen; Richard J O'Connor; Ron Borland; Alexander A Hirsch; Warren K Bickel; Matthew J Carpenter
Journal:  Nicotine Tob Res       Date:  2019-05-21       Impact factor: 4.244

5.  Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes.

Authors:  Natalie Nardone; Eric C Donny; Dorothy K Hatsukami; Joseph S Koopmeiners; Sharon E Murphy; Andrew A Strasser; Jennifer W Tidey; Ryan Vandrey; Neal L Benowitz
Journal:  Addiction       Date:  2016-08-01       Impact factor: 6.526

Review 6.  Effect of Smoking Reduction Therapy on Smoking Cessation for Smokers without an Intention to Quit: An Updated Systematic Review and Meta-Analysis of Randomized Controlled.

Authors:  Lei Wu; Samio Sun; Yao He; Jing Zeng
Journal:  Int J Environ Res Public Health       Date:  2015-08-25       Impact factor: 3.390

Review 7.  The tobacco endgame: a qualitative review and synthesis.

Authors:  Patricia A McDaniel; Elizabeth A Smith; Ruth E Malone
Journal:  Tob Control       Date:  2015-08-28       Impact factor: 7.552

8.  Nicotine Reduction in Cigarettes: Literature Review and Gap Analysis.

Authors:  Micah L Berman; Allison M Glasser
Journal:  Nicotine Tob Res       Date:  2019-12-23       Impact factor: 4.244

9.  Reducing Nicotine Without Misleading the Public: Descriptions of Cigarette Nicotine Level and Accuracy of Perceptions About Nicotine Content, Addictiveness, and Risk.

Authors:  M Justin Byron; Marissa G Hall; Jessica L King; Kurt M Ribisl; Noel T Brewer
Journal:  Nicotine Tob Res       Date:  2019-12-23       Impact factor: 4.244

10.  The effects of maximising the UK's tobacco control score on inequalities in smoking prevalence and premature coronary heart disease mortality: a modelling study.

Authors:  Kirk Allen; Chris Kypridemos; Lirije Hyseni; Anna B Gilmore; Peter Diggle; Margaret Whitehead; Simon Capewell; Martin O'Flaherty
Journal:  BMC Public Health       Date:  2016-04-01       Impact factor: 3.295

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