Literature DB >> 25398471

Outcome of operative treatment of metastatic fractures of the humerus: a systematic review of twenty three clinical studies.

Stein J Janssen1, Teun Teunis, Francis J Hornicek, Jos A M Bramer, Joseph H Schwab.   

Abstract

PURPOSE: This systematic review aims to provide an overview of functional outcome and complications after surgery for metastatic humerus fractures.
METHODS: A literature search was performed in September 2013 using the Pubmed, Embase and Cochrane database. We included 23 studies reporting on 29 treatment arms: intramedullary nailing (19 studies, 596 cases), plate-screw fixation (five studies, 150 cases), endoprosthetic reconstruction (three studies, 81 cases), and diaphysis prosthesis (two studies, 82 cases), totalling 909 fractures. There were 414 pathological and 56 impending fractures. In 439 cases the type of fracture was not specified. Four studies reported functional outcome.
RESULTS: Average Musculoskeletal Tumor Society score ranged from 64 to 79 (three studies, 100 patients) after intramedullary nailing, was 90 (one study, 24 patients) after plate-screw fixation, and 73 (one study, 30 patients) after endoprosthetic reconstruction. Re-operation rate varied from 0 to 10 % after intramedullary nailing (overall 4.4 %), 5-14 % after plate-screw fixation (overall 9.3 %), 14-16 % after diaphysis prosthesis (overall 14.6 %), and 0-6 % after endoprosthetic reconstruction (overall 2.5 %). Systemic complication rate varied between 0 and 26 % after intramedullary nailing (overall 2.2 %), between 0 and 6 % after plate-screw fixation (overall 4.8 %), was 0 % after endoprosthetic reconstruction, and varied between 0 and 16 % after diaphysis prosthesis (overall 9.7 %).
CONCLUSIONS: Reported complication rates help surgeons inform their patients and could aid in surgical decision making. Functional outcome, pain and quality of life were poorly reported. Patient reported outcomes are therefore an important direction for future research.

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Year:  2014        PMID: 25398471     DOI: 10.1007/s00264-014-2584-7

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  48 in total

1.  Femoral metastatic fractures treated with intramedullary nailing.

Authors:  C E Gibbons; S J Pope; J P Murphy; A J Hall
Journal:  Int Orthop       Date:  2000       Impact factor: 3.075

2.  Pathological fractures of the proximal humerus treated with a proximal humeral locking plate and bone cement.

Authors:  H J Siegel; R Lopez-Ben; J P Mann; B A Ponce
Journal:  J Bone Joint Surg Br       Date:  2010-05

3.  Treatment of pathological fractures of the humeral shaft due to bone metastases: a comparison of intramedullary locking nail and plate osteosynthesis with adjunctive bone cement.

Authors:  S Dijkstra; J Stapert; H Boxma; T Wiggers
Journal:  Eur J Surg Oncol       Date:  1996-12       Impact factor: 4.424

4.  Metastatic lesions of the humerus treated with the isoelastic diaphysis prosthesis.

Authors:  M Schürmann; G Gradl; H J Andress; T Kauschke; H Hertlein; G Lob
Journal:  Clin Orthop Relat Res       Date:  2000-11       Impact factor: 4.176

5.  Interlocking intramedullary nailing of pathological fractures of the shaft of the humerus.

Authors:  B J Redmond; J S Biermann; R B Blasier
Journal:  J Bone Joint Surg Am       Date:  1996-06       Impact factor: 5.284

6.  Treatment of pathological fractures of the humerus with a locked intramedullary nail.

Authors:  A J Bauze; M T Clayer
Journal:  J Orthop Surg (Hong Kong)       Date:  2003-06       Impact factor: 1.118

Review 7.  Insight opinion to surgically treated metastatic bone disease: Scandinavian Sarcoma Group Skeletal Metastasis Registry report of 1195 operated skeletal metastasis.

Authors:  Maire Ratasvuori; Rikard Wedin; Johnny Keller; Markus Nottrott; Olga Zaikova; Peter Bergh; Anders Kalen; Johan Nilsson; Halldor Jonsson; Minna Laitinen
Journal:  Surg Oncol       Date:  2013-04-04       Impact factor: 3.279

Review 8.  Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP).

Authors:  Gillian A Hawker; Samra Mian; Tetyana Kendzerska; Melissa French
Journal:  Arthritis Care Res (Hoboken)       Date:  2011-11       Impact factor: 4.794

9.  Metastatic bone disease: a 36-year single centre trend-analysis of patients admitted to a tertiary orthopaedic surgical department.

Authors:  C D Toma; M Dominkus; T Nedelcu; F Abdolvahab; O Assadian; P Krepler; R Kotz
Journal:  J Surg Oncol       Date:  2007-10-01       Impact factor: 3.454

10.  Modular prostheses in the treatment of proximal humerus metastases: review of 40 cases.

Authors:  C Scotti; F Camnasio; G M Peretti; F Fontana; G Fraschini
Journal:  J Orthop Traumatol       Date:  2008-03-13
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  3 in total

1.  Efficacy of a Modified Scoring System to Facilitate Surgical Decision-making for Diaphyseal Malignancies: When is Devitalized Tumor-bearing Autograft of Value?

Authors:  Yu Chen; Xiu-Chun Yu
Journal:  Orthop Surg       Date:  2019-08-11       Impact factor: 2.071

2.  Intramedullary Nailing Versus Plate Osteosynthesis for Humeral Shaft Metastatic Lesions.

Authors:  Marc-Antoine M Ricard; Nikolaos A Stavropoulos; Anas Nooh; Nathalie Ste-Marie; Krista Goulding; Robert Turcotte
Journal:  Cureus       Date:  2021-03-09

Review 3.  A scoping review on the surgical management of metastatic bone disease of the extremities.

Authors:  Joseph K Kendal; Annalise Abbott; Sahil Kooner; Herman Johal; Shannon K T Puloski; Michael J Monument
Journal:  BMC Musculoskelet Disord       Date:  2018-08-06       Impact factor: 2.362

  3 in total

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