Literature DB >> 25397421

Comparison of routine versus targeted HIV testing strategies: coverage and estimated missed infections in emergency room and primary care centre.

María Jesús Pérez Elías1, Cristina Gomez-Ayerbe1, Alfonso Muriel2, Maria Eugenia Calonge3, Alberto Diaz1, Pilar Pérez Elías3, Maria Martinez-Colubi4, Almudena Uranga3, Cristina Santos3, Ana Moreno1, Carmen Quereda1, Enrique Navas1, Santiago Moreno1.   

Abstract

INTRODUCTION: Different HIV Testing Strategies (TS) and clinical care settings had not been face to face evaluated (1). We compared coverage, Newly Diagnosed HIV Infection (NDHI) and Estimated Missing HIV Infections (MHI) in Hospital Emergency Room (HER) and Primary Care Center (PCC), in DRIVE study (Spanish acronym of HIV infection Rapid Diagnosis) and in clinical practice the year before DRIVE.
MATERIALS AND METHODS: In DRIVE study, 18-60 years old, non-HIV-infected population visiting an HER or a PCC were proposed both a structured risk practices and clinical conditions questionnaire (RP&CC-Q) and a rapid HIV test. This arm is the HIV Routine TS. We analyze a hypothetical arm, where risk practices were universally assessed with an RP&CC-Q, subsequently risk-positive patients where HIV tested, Targeted-TS. Coverage was assessed as the ratio of tested population (TP)/attended population (AP) in HER and PCC. TP/AP ratios were also calculated in the year before, the Clinical Practice-TS. NDHI was expressed per ‰ tests performed. MHI was estimated assuming in the non-tested population, overall DRIVE rate of NDHI ‰ and NDHI ‰ in negative RP&CC-Q.
RESULTS: A total of 5329 RP&CC-Q and rapid HIV tests were performed to 49.64% women, median age 37 (28-47) years old, mainly 74.9% Spaniards. Confirmed NDHI was 4.1‰, and in 48, 8% of RP&CC-Q negative NDH was 0‰. HIV screening coverage was always better in PCC than in HER, and higher in DRIVE study than in clinical practice. Estimated MHI was higher in HER and in the clinical practice-TS. Targeted-TS coverage was lower, but resulted in similar NDHI and MHI than routine-TS, testing half the population, see Table 1.
CONCLUSIONS: Best HIV Testing Strategy is routine-TS in Primary Care Center. Targeted-TS resulted in same newly HIV diagnoses and missed HIV infections than routine-TS with half the resources employed.

Entities:  

Year:  2014        PMID: 25397421      PMCID: PMC4225402          DOI: 10.7448/IAS.17.4.19671

Source DB:  PubMed          Journal:  J Int AIDS Soc        ISSN: 1758-2652            Impact factor:   5.396


Coverage, newly diagnosed HIV infections, missed HIV infections
Table 1

Coverage, newly diagnosed HIV infections, missed HIV infections

SettingsHospital emergency roomHospital emergency roomPrimary Care CenterPrimary Care Center
Testing strategiesCoverageNDI‰/no MHICoverageNDI‰/no MHI
Clinical practice 2011/20120.310/1393.72.4/23
DRIVE routine 2012/20132.68.6/12832.92.2/16
DRIVE targeted 2012/20131.438.6/12816.252.2/16
  1 in total

Review 1.  Universal testing and treatment as an HIV prevention strategy: research questions and methods.

Authors:  Richard Hayes; Kalpana Sabapathy; Sarah Fidler
Journal:  Curr HIV Res       Date:  2011-09       Impact factor: 1.581

  1 in total
  3 in total

1.  [Acceptability and feasibility among primary care doctors of the opportunistic search for HIV in Health Care centers in Spain].

Authors:  Rafael Carlos Puentes Torres; Cristina Aguado Taberné; Luis Ángel Pérula de Torres; José Espejo Espejo; Cristina Castro Fernández; Luis Fransi Galiana
Journal:  Aten Primaria       Date:  2017-05-10       Impact factor: 1.137

2.  The impact of nurse-driven targeted HIV screening in 8 emergency departments: study protocol for the DICI-VIH cluster-randomized two-period crossover trial.

Authors:  Judith Leblanc; Alexandra Rousseau; Gilles Hejblum; Isabelle Durand-Zaleski; Pierre de Truchis; France Lert; Dominique Costagliola; Tabassome Simon; Anne-Claude Crémieux
Journal:  BMC Infect Dis       Date:  2016-02-01       Impact factor: 3.090

3.  [Acceptability of the opportunistic search for human immunodeficiency virus infection by serology in patients recruited in Primary Care Centres in Spain].

Authors:  Rafael Carlos Puentes Torres; Cristina Aguado Taberné; Luis Angel Pérula de Torres; José Espejo Espejo; Cristina Castro Fernández; Luís Fransi Galiana
Journal:  Aten Primaria       Date:  2016 Jun-Jul       Impact factor: 1.137

  3 in total

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