Literature DB >> 2539662

Multifunctional Ca2+/calmodulin-dependent protein kinase: domain structure and regulation.

H Schulman, L L Lou.   

Abstract

Cells respond to many hormones, neurotransmitters and growth factors by increasing intracellular Ca2+. This second messenger, in turn, affects cellular function via activation of a novel multifunctional Ca2+/calmodulin-dependent protein kinase. The kinase displays an interesting form of biochemical 'memory'; activation elicits an autophosphorylation which converts it to a Ca2+-independent enzyme that can continue to phosphorylate cellular proteins for some time following termination of the initial Ca2+ stimulus.

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Year:  1989        PMID： 2539662     DOI： 10.1016/0968-0004(89)90045-5

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  30 in total

1.  Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable.

Authors:  T N Davis; J Thorner
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

2.  Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase.

Authors:  F H Cruzalegui; M S Kapiloff; J P Morfin; B E Kemp; M G Rosenfeld; A R Means
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

Review 3.  The 5-HT1A receptor: an overview of recent advances.

Authors:  S el Mestikawy; A Fargin; J R Raymond; H Gozlan; M Hnatowich
Journal:  Neurochem Res       Date:  1991-01       Impact factor: 3.996

4.  Mechanisms underlying intracellular signal transduction of the slow IPSP in submucous neurones of the guinea-pig caecum.

Authors:  S Mihara; K Hirai; Y Katayama; S Nishi
Journal:  J Physiol       Date:  1991-05       Impact factor: 5.182

Review 5.  Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin.

Authors:  C B Klee
Journal:  Neurochem Res       Date:  1991-09       Impact factor: 3.996

6.  Relationship of genes encoding Ca2+/calmodulin-dependent protein kinase Gr and calspermin: a gene within a gene.

Authors:  C A Ohmstede; M M Bland; B M Merrill; N Sahyoun
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-01       Impact factor: 11.205

7.  Possible role for calmodulin and the Ca2+/calmodulin-dependent protein kinase II in postsynaptic neurotransmission.

Authors:  P Siekevitz
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

8.  Gi/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission.

Authors:  Caitlin A Durkee; Ana Covelo; Justin Lines; Paulo Kofuji; Juan Aguilar; Alfonso Araque
Journal:  Glia       Date:  2019-02-23       Impact factor: 7.452

9.  Phosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr.

Authors:  N Sahyoun; O B McDonald; F Farrell; E G Lapetina
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205

10.  Guanine nucleotide binding protein involvement in early steps of phytochrome-regulated gene expression.

Authors:  L C Romero; E Lam
Journal:  Proc Natl Acad Sci U S A       Date:  1993-02-15       Impact factor: 11.205
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