Literature DB >> 25395820

Epilepsy management: newer agents, unmet needs, and future treatment strategies.

C Lee Ventola.   

Abstract

Drug therapy aids most epilepsy patients, but unmet challenges include drug-resistant epilepsy, adverse reactions, drug interactions, the need to better identify epileptic syndromes, and a lack of agents to prevent epilepsy and its comorbidities.

Entities:  

Year:  2014        PMID： 25395820      PMCID： PMC4218673     

Source DB:  PubMed          Journal:  P T        ISSN： 1052-1372


  15 in total

Review 1.  Modern management of epilepsy.

Authors:  J P Leach; H Abassi
Journal:  Clin Med (Lond)       Date:  2013-02       Impact factor: 2.659

Review 2.  Design of innovative therapeutics for pharmacoresistant epilepsy: challenges and needs.

Authors:  Donald F Weaver
Journal:  Epilepsia       Date:  2013-05       Impact factor: 5.864

Review 3.  The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.

Authors:  Rafal M Kaminski; Michael A Rogawski; Henrik Klitgaard
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

Review 4.  Issues related to development of new antiseizure treatments.

Authors:  Karen S Wilcox; Tracy Dixon-Salazar; Graeme J Sills; Elinor Ben-Menachem; H Steve White; Roger J Porter; Marc A Dichter; Solomon L Moshé; Jeffrey L Noebels; Michael D Privitera; Michael A Rogawski
Journal:  Epilepsia       Date:  2013-08       Impact factor: 5.864

Review 5.  Development of new treatment approaches for epilepsy: unmet needs and opportunities.

Authors:  Jacqueline A French; H Steve White; Henrik Klitgaard; Gregory L Holmes; Michael D Privitera; Andrew J Cole; Ellinor Quay; Samuel Wiebe; Dieter Schmidt; Roger J Porter; Alexis Arzimanoglou; Eugen Trinka; Emilio Perucca
Journal:  Epilepsia       Date:  2013-08       Impact factor: 5.864

Review 6.  Drug treatment of epilepsy in adults.

Authors:  Dieter Schmidt; Steven C Schachter
Journal:  BMJ       Date:  2014-02-28

7.  Epilepsy therapy: anticonvulsants, lessons learned and unmet medical needs. Interview by Rona Williamson.

Authors:  Henrik Klitgaard
Journal:  Expert Rev Neurother       Date:  2013-01       Impact factor: 4.618

Review 8.  Epilepsy: new drug targets and neurostimulation.

Authors:  Jorge J Asconapé
Journal:  Neurol Clin       Date:  2013-05-18       Impact factor: 3.806

Review 9.  Antiepileptic drug treatment: new drugs and new strategies.

Authors:  Jacqueline A French; Deana M Gazzola
Journal:  Continuum (Minneap Minn)       Date:  2013-06

Review 10.  Research advances in basic mechanisms of seizures and antiepileptic drug action.

Authors:  Władysław Lasoń; Małgorzata Chlebicka; Konrad Rejdak
Journal:  Pharmacol Rep       Date:  2013       Impact factor: 3.024
View more
  11 in total

1.  Multiple-Ascending Dose Study in Healthy Subjects to Assess the Pharmacokinetics, Tolerability, and CYP3A4 Interaction Potential of the T-Type Calcium Channel Blocker ACT-709478, A Potential New Antiepileptic Drug.

Authors:  Muriel Richard; Priska Kaufmann; Marion Ort; Rüdiger Kornberger; Jasper Dingemanse
Journal:  CNS Drugs       Date:  2020-03       Impact factor: 5.749

Review 2.  Lacosamide: A Review in Focal-Onset Seizures in Patients with Epilepsy.

Authors:  Sheridan M Hoy
Journal:  CNS Drugs       Date:  2018-05       Impact factor: 5.749

Review 3.  Brivaracetam: A Review in Partial-Onset (Focal) Seizures in Patients with Epilepsy.

Authors:  Sheridan M Hoy
Journal:  CNS Drugs       Date:  2016-08       Impact factor: 5.749

Review 4.  Lacosamide: A Review in Focal Seizures in Patients with Epilepsy.

Authors:  Lesley J Scott
Journal:  Drugs       Date:  2015-12       Impact factor: 9.546

Review 5.  Pharmacological and Therapeutic Approaches in the Treatment of Epilepsy.

Authors:  Shampa Ghosh; Jitendra Kumar Sinha; Tarab Khan; Kuramkote Shivanna Devaraju; Prabhakar Singh; Kumar Vaibhav; Pankaj Gaur
Journal:  Biomedicines       Date:  2021-04-25

6.  Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model.

Authors:  Samantha L Hodges; Paige D Womble; Eliesse M Kwok; Alyssa M Darner; Savannah S Senger; Matthew S Binder; Amanda M Faust; Siena M Condon; Suzanne O Nolan; Saul I Quintero; Joaquin N Lugo
Journal:  Behav Brain Res       Date:  2021-04-25       Impact factor: 3.352

7.  Real life pharmaceutical treatment patterns for adult patients with focal epilepsy in Germany: a longitudinal and cross-sectional analysis of recently approved anti-epileptic drugs.

Authors:  Antje Groth; Thomas Wilke; Simon Borghs; Patrick Gille; Lars Joeres
Journal:  Ger Med Sci       Date:  2017-06-12

8.  Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

Authors:  Jo Sourbron; Ilse Smolders; Peter de Witte; Lieven Lagae
Journal:  Front Pharmacol       Date:  2017-04-06       Impact factor: 5.810

Review 9.  Montelukast: The New Therapeutic Option for the Treatment of Epilepsy.

Authors:  Bekalu Amare Tesfaye; Haftom Gebregergs Hailu; Kaleab Alemayehu Zewdie; Muluken Altaye Ayza; Derbew Fikadu Berhe
Journal:  J Exp Pharmacol       Date:  2021-01-20

10.  Brivaracetam Retention Rate and Seizure Outcomes in Patients with Drug-Resistant Focal Epilepsy Included in the Medical Need Program in Belgium: A Real-World, Multicenter, Chart Review.

Authors:  Chantal Depondt; Wim Van Paesschen; Kenou van Rijckevorsel; Iryna Leunikava; France Ferrière
Journal:  Drugs Real World Outcomes       Date:  2021-05-31
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.