V Nobili1, C Della Corte1, D Liccardo1, A Mosca2, R Caccamo3, G S Morino4, A Alterio1, F De Peppo3. 1. HepatoMetabolic Department, Liver Research Unit, 'Bambino Gesù' Children's Hospital, Rome, Italy. 2. Center of Dietetics and Nutrition, Pediatric Clinic, 'La Sapienza' University, Rome, Italy. 3. Division of Pediatric Surgery, Department of Surgery, 'Bambino Gesù' Children's Hospital, Rome, Italy. 4. Unit of Clinical Nutrition, 'Bambino Gesù' Children's Hospital, Rome, Italy.
Abstract
BACKGROUND: Lifestyle interventions are often ineffective in the treatment of pediatric obesity. Weight loss devices have been introduced for the temporary nonsurgical treatment of morbid obesity. OBJECTIVE: The aim of the study is to evaluate the efficacy of Obalon Intragastric Balloon on weight loss and on metabolic and cardiovascular parameters in a pediatric population with severe obesity. METHODS: We enrolled 10 children with severe obesity. In all patients anthropometric parameters, biochemical tests, ultrasound liver examination and blood pressure monitoring were evaluated at the time of insertion and after removal of device. RESULTS: The Obalon had a positive effect on decrease of weight, body mass index and percentage of excess body weight within 3 months from placement. Moreover, this safe minimally invasive device improves the cardio-metabolic profiles of obese children. CONCLUSIONS: The Obalon could be a useful tool in the difficult management of pediatric patients with morbid obesity, inducing in short-term a meaningful weight loss.
BACKGROUND: Lifestyle interventions are often ineffective in the treatment of pediatric obesity. Weight loss devices have been introduced for the temporary nonsurgical treatment of morbid obesity. OBJECTIVE: The aim of the study is to evaluate the efficacy of Obalon Intragastric Balloon on weight loss and on metabolic and cardiovascular parameters in a pediatric population with severe obesity. METHODS: We enrolled 10 children with severe obesity. In all patients anthropometric parameters, biochemical tests, ultrasound liver examination and blood pressure monitoring were evaluated at the time of insertion and after removal of device. RESULTS: The Obalon had a positive effect on decrease of weight, body mass index and percentage of excess body weight within 3 months from placement. Moreover, this safe minimally invasive device improves the cardio-metabolic profiles of obesechildren. CONCLUSIONS: The Obalon could be a useful tool in the difficult management of pediatric patients with morbid obesity, inducing in short-term a meaningful weight loss.
Authors: Aaron S Kelly; Marsha D Marcus; Jack A Yanovski; Susan Z Yanovski; Stavroula K Osganian Journal: Int J Obes (Lond) Date: 2018-10-03 Impact factor: 5.095
Authors: Francesco De Peppo; Romina Caccamo; Ottavio Adorisio; Emanuela Ceriati; Paola Marchetti; Antonio Contursi; Arianna Alterio; Claudia Della Corte; Malnia Manco; Valerio Nobili Journal: Endosc Int Open Date: 2017-01
Authors: Michelle I Cardel; Mark A Atkinson; Elsie M Taveras; Jens-Christian Holm; Aaron S Kelly Journal: JAMA Pediatr Date: 2020-06-01 Impact factor: 16.193