Literature DB >> 25393563

Obesity, adipokines and cancer: an update.

C H Lee1, Y C Woo1, Y Wang2,3,4, C Y Yeung1, A Xu1,2,3,4, K S L Lam1,3,4.   

Abstract

Obesity causes dysfunction of adipose tissue, with resultant chronic inflammation and adverse interplay of various adipokines, sex steroids and endocrine hormones. All these drive tumourigenesis and explain the epidemiological link between obesity and cancer. Over the past decade, the associations among obesity, adipokines and cancer have been increasingly recognized. Adipokines and their respective signalling pathways have drawn much research attention in the field of oncology and cancer therapeutics. This review will discuss the recent advances in the understanding of the association of several adipokines with common obesity-related cancers and the clinical therapeutic implications.
© 2014 John Wiley & Sons Ltd.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25393563     DOI： 10.1111/cen.12667

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  28 in total

Review 1.  Modifiable Host Factors in Melanoma: Emerging Evidence for Obesity, Diet, Exercise, and the Microbiome.

Authors:  Allison Betof Warner; Jennifer L McQuade
Journal:  Curr Oncol Rep       Date:  2019-07-01       Impact factor: 5.075

Review 2.  The Role of Adipokines in Breast Cancer: Current Evidence and Perspectives.

Authors:  Gerasimos Socrates Christodoulatos; Nikolaos Spyrou; Jona Kadillari; Sotiria Psallida; Maria Dalamaga
Journal:  Curr Obes Rep       Date:  2019-12

3.  Analysis of circulating adipokines in patients newly diagnosed with solid cancer: Associations with measures of adiposity and tumor characteristics.

Authors:  Nehad Ayoub; Mohammad Alkhatatbeh; Malak Jibreel; Mera Ababneh
Journal:  Oncol Lett       Date:  2017-02-01       Impact factor: 2.967

Review 4.  Classic and Novel Adipocytokines at the Intersection of Obesity and Cancer: Diagnostic and Therapeutic Strategies.

Authors:  Nikolaos Spyrou; Konstantinos I Avgerinos; Christos S Mantzoros; Maria Dalamaga
Journal:  Curr Obes Rep       Date:  2018-12

Review 5.  Interaction between adipose tissue and cancer cells: role for cancer progression.

Authors:  Jean-François Dumas; Lucie Brisson
Journal:  Cancer Metastasis Rev       Date:  2020-10-02       Impact factor: 9.264

6.  Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain.

Authors:  Kalavathi Dasuri; Le Zhang; Sun O K Fernandez Kim; Annadora J Bruce-Keller; Jeffrey N Keller
Journal:  Biochim Biophys Acta       Date:  2015-11-10

7.  Obesity-Dependent Adipokine Chemerin Suppresses Fatty Acid Oxidation to Confer Ferroptosis Resistance.

Authors:  Sze Kiat Tan; Iqbal Mahmud; Flavia Fontanesi; Michelle Puchowicz; Chase K A Neumann; Anthony J Griswold; Rutulkumar Patel; Marco Dispagna; Hamzah H Ahmed; Mark L Gonzalgo; J Mark Brown; Timothy J Garrett; Scott M Welford
Journal:  Cancer Discov       Date:  2021-03-23       Impact factor: 39.397

8.  Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.

Authors:  Jin Wang; Fachen Zhou; Fengzhou Li; Bing Wang; Yiying Hu; Xia Li
Journal:  Ann Transl Med       Date:  2021-04

9.  ERK2 and Akt are negative regulators of insulin and Tumor Necrosis Factor-α stimulated VCAM-1 expression in rat aorta endothelial cells.

Authors:  Gregory B Pott; Mark Tsurudome; Nadia Bamfo; Marc L Goalstone
Journal:  J Inflamm (Lond)       Date:  2016-02-25       Impact factor: 4.981

Review 10.  Visceral Adiposity and Cancer: Role in Pathogenesis and Prognosis.

Authors:  Lucilla Crudele; Elena Piccinin; Antonio Moschetta
Journal:  Nutrients       Date:  2021-06-19       Impact factor: 5.717
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.