S Whitehouse1, J Stephenson2, V Sinclair3, J Gregory4, A Tambe5, R Verma6, Irfan Siddique7, Mohammad Saeed8. 1. ST7 Orthopaedics, North West Deanery, Manchester, UK. samjw@doctors.org.uk. 2. School of Human and Health Sciences, University of Huddersfield, Huddersfield, UK. j.stephenson@hud.ac.uk. 3. ST7 Orthopaedics, North West Deanery, Manchester, UK. vicfsinclair@doctors.org.uk. 4. University of Manchester, Manchester, UK. Jonathan.gregory@cmft.nhs.uk. 5. Salford Royal Foundation Trust, Salford, UK. Anant.tambe@srft.nhs.uk. 6. Salford Royal Foundation Trust, Salford, UK. Rajat.verma@srft.nhs.uk. 7. Salford Royal Foundation Trust, Salford, UK. irfan.siddique@srft.nhs.uk. 8. Salford Royal Foundation Trust, Salford, UK. mohammad.saeed@srft.nhs.uk.
Abstract
PURPOSE: The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC). METHODS: We analysed the data of 100 patients undergoing surgical intervention for MSCC at a tertiary spinal unit and recorded the primary tumour pathology and Karnofsky performance status to calculate the OSRI. Logistic regression models and survival plots were applied to the data in accordance with the original paper. RESULTS: Lower OSRI scores predicted longer survival. The OSRI score predicted survival accurately in 74% of cases (p = 0.004). CONCLUSIONS: Our study has found that the OSRI is a significant predictor of survival at levels similar to those of the original authors and is a useful and simple tool in aiding complex decision making in patients presenting with MSCC.
PURPOSE: The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC). METHODS: We analysed the data of 100 patients undergoing surgical intervention for MSCC at a tertiary spinal unit and recorded the primary tumour pathology and Karnofsky performance status to calculate the OSRI. Logistic regression models and survival plots were applied to the data in accordance with the original paper. RESULTS: Lower OSRI scores predicted longer survival. The OSRI score predicted survival accurately in 74% of cases (p = 0.004). CONCLUSIONS: Our study has found that the OSRI is a significant predictor of survival at levels similar to those of the original authors and is a useful and simple tool in aiding complex decision making in patients presenting with MSCC.
Authors: Robert Pearse Piggott; Mark Curtin; Sudarshan Munigangaiah; Mutaz Jadaan; John Patrick McCabe; Aiden Devitt Journal: World J Orthop Date: 2017-06-18